1. Volume 101, Issue 4, Pages 487-498 (April 2006)
Ultrastructural changes of the palatal mucosa following application of 4-nitroquinoline-l- oxide (4NQO) in rats subjected to major salivary gland excision 
Antonia Sioga, MD, PhD, Louise Economou, MD, PhD, Eleftherios G. Kaklamanos, DDS, Vasilios Antoniades, DDS, George Keramidas, MD, Anastasios Manthos, MD, PhD, Kostantinos Antoniades, MD, DDS, PhD 
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics 
Volume 101, Issue 4, Pages (April 2006)
DOI: /j.tripleo
Copyright © 2006 Mosby, Inc. Terms and Conditions

2. Fig. 1
Group A. 13 weeks. Basal layers of epithelium with increased intercellular spaces () and reduction of hemidesmosomes () (×8000).
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics  , DOI: ( /j.tripleo )
Copyright © 2006 Mosby, Inc. Terms and Conditions

3. Fig. 2
Group A. 16 weeks. Basal cytoplasmic processes (). N: nucleus of the cuboidal basal cells (×5000).
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics  , DOI: ( /j.tripleo )
Copyright © 2006 Mosby, Inc. Terms and Conditions

4. Fig. 3
Group A. 16 weeks. Accumulation of desmosomes (d) between the cells of middle layers, bundle of tonofilaments (f) in the cytoplasm (×16 000).
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics  , DOI: ( /j.tripleo )
Copyright © 2006 Mosby, Inc. Terms and Conditions

5. Fig. 4
Group A. 23 weeks. Accumulation of damaged desmosomes (d), bundles of tonofilaments (f) in cells of middle layers, with high nucleocytoplasmic index (N) (×8000).
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics  , DOI: ( /j.tripleo )
Copyright © 2006 Mosby, Inc. Terms and Conditions

6. Fig. 5
Group A. 23 weeks. The basement membrane is discontinuous (), the basal cytoplasmic processes are very large (), there are a lot of tonofilaments (f) in middle and basal cells, with high nucleocytoplasmic index and well-developed nucleolus (n). c, capillary in the connective tissue. A grey line has been drawn to emphasize the discontinuity of the basement membrane (×6000).
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics  , DOI: ( /j.tripleo )
Copyright © 2006 Mosby, Inc. Terms and Conditions

7. Fig. 6
Group B. 13 weeks. Epithelium (E) with many layers of flat cells, basement membrane (), connective tissue (ct) (×4000).
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics  , DOI: ( /j.tripleo )
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8. Fig. 7
Group B. 13 weeks. The basal cells have many bundles of tonofilaments (f), high nucleocytoplasmic index, and large nucleus with well-developed nucleolus (n). The basement membrane is discontinuous (). A grey line has been drawn to emphasize the discontinuity of the basement membrane (×6000).
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics  , DOI: ( /j.tripleo )
Copyright © 2006 Mosby, Inc. Terms and Conditions

9. Fig. 8
Group B. 10 weeks. Increased intercellular spaces () in the middle layers of epithelium (×4000).
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics  , DOI: ( /j.tripleo )
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10. Fig. 9
Group B. 20 weeks. Large basal cytoplasmic processes (), discontinuous basement membrane (). A grey line has been drawn to emphasize the discontinuity of the basement membrane (×10 000).
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics  , DOI: ( /j.tripleo )
Copyright © 2006 Mosby, Inc. Terms and Conditions

11. Fig. 10
Group B. 16 weeks. The cells are separated, with pleomorphic nucleus (N) and mitotic figures (M), discontinuous basement membrane (). A grey line has been drawn to emphasize the discontinuity of the basement membrane (×4000).
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics  , DOI: ( /j.tripleo )
Copyright © 2006 Mosby, Inc. Terms and Conditions

12. Fig. 11
Group B. 25 weeks. Large nuclei with prominent multiple nucleoli (n), pyknotic nuclei (N) (×4000).
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics  , DOI: ( /j.tripleo )
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13. Fig. 12
Group B. 23 weeks. The basement membrane is discontinuous () in a large part of epithelium (×20 000).
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics  , DOI: ( /j.tripleo )
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14. Fig. 13
Group C. Animals with major salivary glands. Middle layer cells. N: nuclei. (×4000).
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics  , DOI: ( /j.tripleo )
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15. Fig. 14
Group C. Animals subjected to major salivary glands excision. Middle layer cells. : lightly dilated intercellular spaces (×4000).
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics  , DOI: ( /j.tripleo )
Copyright © 2006 Mosby, Inc. Terms and Conditions

16. Fig. 15
Group C. Animals subjected to major salivary glands excision. Keratin layer. (×4000).
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics  , DOI: ( /j.tripleo )
Copyright © 2006 Mosby, Inc. Terms and Conditions