1. EYELID EDEMA AND FILAMENTARY KERATITIS AS HYPERACUTE DEBUT OF PRYMARY SJÖGREN´S SYNDROME IN YOUNG PATIENT
Borja Maroto Rodríguez
Esther Corredera Salinero
Pila Puy Gallego
María Isabel Gabarrón
Raul Veiga Cabello
Hospital Universitario de Fuenlabrada

2. - Artificial tear drops - Topical corticosteroids
Woman 34 years.
Red eyes and bilateral eyelid edema.
AV 1 both eyes.
Allergic disease ?????
- Artificial tear drops
- Topical corticosteroids

3. Two weeks Systemic evaluation: ANAs 1/80 Shirmer Test: 1 mm both eyes
Gland Biopsy: Moderate lymphocytic inflammatory component.
PRYMARY SJÖGREN´S SYNDROME
DEFLAZACORT
METOTREXATE

4. Two months Clinical improvement of dry eyes and eyelid inflammation.
RITUXIMAB

5. CONCLUSIONES Classification criteria for Primary sjögren´s syndrome
1- ocular symptoms: dry eyes
2- oral symptoms: dry mouth
3- ocular signs: Shirmer, rose bengala
4- Histopathology (salivary gland)
5- Salivary gland involvement (sialography, salivary flow)
6- Autoantibodies: antiRo (SSA), anti La (SSB) o ANA > 1:320
Early anti-inflammatory-immune therapy can improve ocular signs and symptoms in Primary sjögren´s syndrome.