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Tobacco / Nicotine
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Introduction Smoking most avoidable cause of death
1,000 Americans die each day due to tobacco related diseases – 1 in 6 deaths smoking related Tobacco companies spend 50 times more $$ in advertising than the government does in anti-smoking ads Should advertising be banned? Why do people begin smoking?
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Pharmacology Nicotine is the addictive substance Administration
Inhalation Sublingual Absorption – directly into bloodstream Affects brain & CNS Action Causes a release of norepinephrine – stimulant Affects catecholamine – affects HR & BP Nicotine at high levels act as a depressant 50% of nicotine is metabolized in 30 min.
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Physiological Effects
Increase heart rate Increase blood pressure Increase breathing rate Increase cardiac output Increase brain activity – increase concentration, memory Decrease appetite Psychological effects?
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Addiction Physical Psychological Withdrawal symptoms
Need to maintain a functional level of nicotine Psychological Withdrawal symptoms Craving, irritability, anxiety, restlessness, difficulty concentrating, change in appetite Peak at 1-2 days Negative reinforcement
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Adverse Effects Cardiovascular Respiratory Cancer
Most modifiable risk factor for H.D. Due to carbon monoxide buildup Atheroscherosis Respiratory Damage to cilia Chronic Obstructive Lung Disease – emphysema, bronchitis Cancer Lung cancer Other cancers
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Benefits of Quitting Decrease risk of cancer Increase life expectancy
Decrease risk of stroke, chronic cough Save $$$$ Concerns of quitting Gain weight
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To Quit Smoking Knowledge about health risks
Recognition that health risks are applicable Familiar with steps to quit Patch/gum Support/encouragement Learn to handle stress/urges Decrease risk factors Belief that benefits outweigh the pleasure Certainty that one can start and maintain behavior required to stop
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Smokers Rights Environmental tobacco smoke (ETS) – Passive smoke
Class A carcinogen Mainstream smoke Sidestream smoke S/S – stress, discomfort, cough, wheeze, allergy Is restricting cigarettes (smoking) legal?
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Smokeless Tobacco Chewing tobacco & snuff
1.8 million users – mostly young males, athletes Nicotine w/o exposure to CO & tar Same physiological effects as smoking Time-released absorption Other health problems Gum disease, damage to enamel “Leukoplakia” Risk of oral, gum, & cheek cancers Smokeless tobacco doesn’t injure others
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