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Nervous System
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Nervous System: Neurons
Neurons are masses of nerve cells that transmit information to other nerves, tissues or cells (nerve impulses). Consists of 1. cell body- contains the nucleus and two extensions. 2. dendrites- shorter, more numerous, receive information. (carry to the cell body) 3. Axons- single, long fiber which conducts impulses away from the cell body.
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There are two parts to the nervous system:
Central nervous system (CNS) Consists of the brain and spinal cord Peripheral Nervous System (PNS) Includes 31 pairs of spinal nerves Includes 12 pairs of cranial nerves
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Functions of the Nervous System
1. Sensory Function- gathers information within and around the body, sends nerve impulses to the CNS. 2. Integrative function- information is interpreted, to create sensations, create thoughts, add to memory, make decisions, etc. 3. Motor Function- responds to signals (impulses). Signals go from the CNS to effectors (muscles or glands).
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Brain Integration center of the body
Constant input from sensory organs Constant learning Memory of response or outcome Huge collection of myelinated and unmyelinated neurons Divided into lobes: different sensory and motor functions are controlled by different lobes.
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Brain Three major parts:
Cerebrum: largest, sensory and motor functions, higher mental function (memory, reasoning) Cerebellum- coordinate voluntary muscles Brain stem- regulate visceral functions
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Brain Sulci and gyri are along the surface Sulci are shallow grooves
Gyri are ridges or bumps Fissures are deep grooves
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Brain
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Parietal lobe: input lobe
Major sensory lobe Hard drive/memory Speech understanding-Broca’s area Recognition of people, places, items, events, etc. Memory of outcomes taste
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More lobes: Occipital lobe: Temporal lobe: Cerebellum:
Receives input from the eyes and sends it to the parietal lobe for interpretation Temporal lobe: receives input from the ears and sends it to the parietal lobe for interpretation memory processing –short term Cerebellum: fine motor coordination balance and posture *increases its control with practice
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Brain stem 1. midbrain: 2. pons: 3. medulla oblongata:
auditory and visual reflexes eye movement fluidity of movement 2. pons: integration center for cerebellum and cerebral communication respiratory center 3. medulla oblongata: involuntary muscle control autonomic reflexes respiratory/cardiovascular center vomiting, coughing, hiccupping, sneezing, swallowing
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Nervous system division
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Cells of the nervous System: Neurons
The neuron: Large, complex cells Longevity: long life Lack centrioles- cannot perform mitosis Classified by structure and function
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Parts of a neuron Cell body: contains the nucleus and all other cellular organelles along with the bulk of cytoplasm Dendrites: receptive or input regions that provide enormous surface area for receiving signals from receptor organs/glands Axon: in each neuron, there is only one! It can be very long or so short it seems nonexistent. Conduction component that generates and propagates nerve impulses away from the cell body.
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More parts of a neuron…. Myelin: fatty covering that insulates the axon. Gaps between myelin are called nodes of Ranvier. 2-4 mph without myelin 250 mph with myelin Axon terminal: end of the axon where neurotransmitters are stored and released.
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Functional classification of a neuron (how it reacts in the body)
Sensory: receive impulses and transmit to the brain -afferent neurons Motor: receive impulses from the brain and send them to effector organs -efferent neurons Interneuron: communicate between motor and sensory along the spinal cord -association neurons
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Structural Classification of a neuron
Multipolar: 3 or more attachments to the cell body *** most common structure Bipolar: 2 attachments to the cell body *** rare- special senses Unipolar: 1 attachment to the cell body *** rare- PNS sensations
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Cells of the nervous System: Neuroglial Cells
Supportive tissue of the nervous system (more numerous than neurons) 5 types: Microglial cells Oligodendrites Astrocytes Ependymal cells Schwann cells
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More neuroglia: Oligodendrocyte: in CNS Ependymal: In CNS
Branching cells Wrap their branches around the neuron’s axon insulating it with myelin Ependymal: In CNS Epithelial cells Produce and form a barrier between neurons and CSF
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Neuroglia Astrocyte –in CNS Microglia- in CNS Small, branching cell
Most abundant neuroglia Braces neurons to capillaries- exchanges between neurons and capillaries Microglia- in CNS Thorny cells Monitors neuron health
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More neuroglia: Satellite Cell: in PNS Schwann Cell: in PNS
Looks like moons or satellites Job is still unknown but thought to act as astrocytes Schwann Cell: in PNS Has branching extensions like oligodendrocytes Wraps its branches around PNS neuron axons to insulate them with myelin
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Nerve impulses Nerve impulse: propagation of an impulse from dendrite to axon terminal Resting membrane potential: high concentration of sodium ions outside the membrane and a high concentration of potassium inside the cell. Na/K channel vs Na/K pump: channels are open and allow ions to flow freely while pumps turn off and on to reset the membrane potential
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Depolarization: neuron membrane is more permeable to sodium ions. * Na+ flows into the neuron Repolarization: neuron membrane is more permeable to potassium ions. *K+ flows out of the neuron Hyperpolarization: too much potassium leaves making the neuron too negative ~ -90mV After hyperpolarization,- sodium/potassium pumps reset the resting membrane potential.
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