1. Estimating the monetary impact of the project
D.A. Sarigiannis1,2
1 Environmental Engineering Laboratory
Department of Chemical Engineering,
Aristotle University of Thessaloniki
GR-54124, Thessaloniki, Greece
2 Chair of Environmental Health Engineering,
Institute of Advanced Study, Pavia 27100, Italy

2. Steps Estimate previous exposure levels
Account for multiple routes (if relevant)
Age and gender differentiated
Use of a dose-response (CRF, slope factor…….)
Estimate relative risk
Identify size of affected population
Estimate impact
Estimate DALYs (see following tables)
Estimate reduced exposure after the CROME intervention
……………………
Estimate Avoided DALYs
Translate avoided DALYs into monetary values
Assume 1 DALY = 3 times GDP (WHO suggestion, to be checked)

3. DALYs Disease type YLLe (y) YLDe (y) DALYe (y) Cancer
Mouth and oropharynx cancer
5.7
0.5
6.2
Oesophagus cancer
17.6
0.4
17.9
Stomach cancer 13
0.6
13.6
Colon and rectum cancer 8
0.8
8.8
Liver cancer
22.1
22.5
Pancreas cancer
15.9
0.3
16.2
Trachea, bronchus and lung cancer
16.5
Melanoma and other skin cancer
6.1
0.2
6.3
Breast cancer
7.2
7.6
Cervix uteri cancer
11.7
12.0
Corpus uteri cancer
3.7
4.0
Ovary cancer
13.3
Prostate cancer
3.3
3.9
Bladder cancer
4.6
5.0
Lymphomas and multiple myeloma
13.9
14.2
Leukemia 28
28.3
Cancer average
11.0
11.5
Neuropsychiatric conditions
Bipolar disorder
0.1
0.7
Schizophrenia
1.9
23.4
25.3
Epilepsy
Dementia
1.3 5
Parkinson disease
1.8
4.7
6.5
Multiple sclerosis
13.2
19.7
Obsessive-compulsive disorder
Panic disorder
Neurodevelopmental disorders
Cognitive impairment
5.9
Mental retardation
24.5
1.1
Cardiovascular diseases
Rheumatic heart disease
19.2
20.5
Ischemic heart disease
8.5
9.2
Cerebrovascular heart disease 11
12.2
Inflammatory heart disease
5.5
Respiratory diseases
Chronic obstructive pulmonary disease
3.2
8.2
Asthma
Diabetes mellitus
0.9
2.2

4. DALYs Disease type YLLe (y) YLDe (y) DALYe (y) Digestive diseases
Peptic ulcer
0.6
0.3
1.0
Liver cirrhosis 17
2.6
19.5
Genitourinary diseases
Nephritis and nephrosis
11.6
0.8
12.4
Benign prostate hypertrophy
0.04
0.4
Musculoskeletal diseases
Rheumatoid arthritis
0.1
1.4
1.5
Osteoarthritis
2.7
Congenital anomalies
Abdominal wall defect 45
Anencephaly 80
Anorectal atresia 16
0.2
16.2
Cleft lip
3.6
6.2
Cleft palate
5.8
7.8
13.6
Oesophageal atresia
Renal agenesis
Down syndrome
36.4
55.9
Congenital heart anomalies
18.5
20.1
38.6
Spina bifida 32
37.9
69.9