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Comparative systematic review and meta-analysis of compression modalities for the promotion of venous ulcer healing and reducing ulcer recurrence  Karen.

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Presentation on theme: "Comparative systematic review and meta-analysis of compression modalities for the promotion of venous ulcer healing and reducing ulcer recurrence  Karen."— Presentation transcript:

1 Comparative systematic review and meta-analysis of compression modalities for the promotion of venous ulcer healing and reducing ulcer recurrence  Karen F. Mauck, MD, MS, Noor Asi, MD, Tarig A. Elraiyah, MBBS, Chaitanya Undavalli, MBBS, Mohammed Nabhan, MD, Osama Altayar, MD, Mohamad Bassam Sonbol, MD, Larry J. Prokop, MLS, Mohammad Hassan Murad, MD, MPH  Journal of Vascular Surgery  Volume 60, Issue 2, Pages 71S-90S.e2 (August 2014) DOI: /j.jvs Copyright © 2014 Society for Vascular Surgery Terms and Conditions

2 Fig 1 Study selection process. 4LB, Four-layer bandage; LLB, long stretch bandage; RCT, randomized controlled trial; SSB, short stretch bandage. Journal of Vascular Surgery  , 71S-90S.e2DOI: ( /j.jvs ) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

3 Fig 2 The solid squares denote the relative risk, the horizontal lines represent the 95% confidence intervals (CIs), and the diamond denotes the pooled relative risk. Random effects model; I2 = Test for overall effect Z = 1.2 (P = .23). Journal of Vascular Surgery  , 71S-90S.e2DOI: ( /j.jvs ) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

4 Fig 3 The solid squares denote the relative risk, the horizontal lines represent the 95% confidence intervals (CIs), and the diamond denotes the pooled relative risk. Random effects model; I2 = 19.7 Test for overall effect Z = 2.1 (P = .03). Journal of Vascular Surgery  , 71S-90S.e2DOI: ( /j.jvs ) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

5 Fig 4 The solid squares denote the relative risk, the horizontal lines represent the 95% confidence intervals (CIs), and the diamond denotes the pooled relative risk. Random effects model; I2 = 0. Test for overall effect Z = −0.54 (P = .59). Journal of Vascular Surgery  , 71S-90S.e2DOI: ( /j.jvs ) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

6 Fig 5 The solid squares denote the mean difference, the horizontal lines represent the 95% confidence intervals (CIs), and the diamond denotes the weighted mean difference. Random effects model; I2 = Test for overall effect Z = −0.14 (P = .89). Journal of Vascular Surgery  , 71S-90S.e2DOI: ( /j.jvs ) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

7 Fig 6 The solid squares denote the relative risk, the horizontal lines represent the 95% confidence intervals (CIs), and the diamond denotes the pooled relative risk. Random effects model; I2 = 0. Test for overall effect Z = 0.21 (P = .83). Journal of Vascular Surgery  , 71S-90S.e2DOI: ( /j.jvs ) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

8 Fig 7 The solid squares denote the relative risk, the horizontal lines represent the 95% confidence intervals (CIs), and the diamond denotes the pooled relative risk. Random effects model; I2 = 0. Test for overall effect Z = −0.51 (P = .61). Journal of Vascular Surgery  , 71S-90S.e2DOI: ( /j.jvs ) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

9 Fig 8 The solid squares denote the mean difference, the horizontal lines represent the 95% confidence intervals (CIs), and the diamond denotes the weighted mean differences. Random effects model; I2 = 0. Test for overall effect Z = −1.63 (P = .10). Journal of Vascular Surgery  , 71S-90S.e2DOI: ( /j.jvs ) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

10 Fig 9 The solid squares denote the mean difference, the horizontal lines represent the 95% confidence intervals (CIs), and the diamond denotes the weighted mean difference. Random effects model; I2 = 0. Test for overall effect Z = 0.04 (P = .97). Journal of Vascular Surgery  , 71S-90S.e2DOI: ( /j.jvs ) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

11 Fig 10 Exploration of publication bias using a funnel plot. Each circle represents the effect size from a study. The tests for funnel symmetry are not statistically significant suggesting against publication bias. Journal of Vascular Surgery  , 71S-90S.e2DOI: ( /j.jvs ) Copyright © 2014 Society for Vascular Surgery Terms and Conditions


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