1. Warm-Up (12/09)
On the piece of white paper from the back, answer the following question.
Name
Date
Period
Explain how low insulin levels lead to increased glucose secretion into the blood in the context of cell communication. Be sure to include a discussion on a change in gene expression.

2. The Immune System: war in your body
Mission: ID the enemy, then kill it.
Method: make antibodies that recognize the enemy’s flag (the antigen)

3. The Immune System: war in your body
the spies: B cells
the enemy: pathogens
antibody
antigen

4. The Immune System: war in your body
the enemy: pathogens
the soldiers: T cells

5. The Immune System: war in your body
the enemy: pathogens
the soldiers: T cells

6. The Immune System: war in your body
the enemy: pathogens
the soldiers: T cells
nucleus
antibody receptor
poison genes
Death proteins released

7. Critical Thinking Question #1
Discuss this question with your partner and write or represent it. I will call on three people to share their partners’ answers.
Explain how cells of the immune system communicate with other cells.

8. The Immune System: war in your body
nucleus

9. The Immune System: war in your body
Humoral System
Cell-Mediated System
antibody
antigen
B cells make antibodies against specific antigens
T cells, a type of white blood cells, recognize antibodies and kill the pathogens.

10. The Immune System: war in your body
Humoral System
New antibodies are custom-made for every new antigen
B cells make antibodies against specific antigens

11. The Immune System: war in your body
Cell-Mediated System
antibody
antigen
Once antibodies are made, a second exposure to the same antigen results in an enhanced response.
T cells, a type of white blood cells, recognize antibodies and kill the pathogens.

12. Case in Point: Vaccines
Dead pathogen with antigen attached →
B cells make antibodies →
fast T-cell response next time.
Yo, that don’t look like a lollypop, and it definitely don’t feel like a lollypop!
Examples: influenza (flu) hepatitis C tetanus meningitis

13. Case in Point: Blood Types
Blood types can be A, AB, B, or O depending which antigens are present on your blood cells.
Organ donations can also fail because the wrong antigens are present on the donor organs.

14. Critical Thinking Question #2
Discuss this question with your partner and write or represent it. I will call on three people to share their partners’ answers.
Create a representation (cartoon, diagram, et cetera) comparing and contrasting the cell-mediated and humoral response.

15. Closure
On the piece of white paper from the back, answer the following question:
Name
Date
Period
Compare the immune response to cell signaling: which components are analogous to ligands, receptors, and cellular response?
Scale 1 – 10