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Kidney Function I Anatomy Kidney Function II Kidney Disorders Potpourri 100 100 100 100 100 200 200 200 200 200 300 300 300 300 300 400 400 400 400 400 500 500 500 500 500
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What are the three functions of the Kidney?
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Remove Wastes 2. Maintain Water Balance 3. Maintain Ion / pH Balance
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Name three components of blood that do not make it past the glomerular filter.
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RBC’s, WBC’s, platelets, large proteins
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In osmosis, water moves from an area of ______ concentration to an area of _____ concentration.
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Water moves from high concentration to low concentration
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Where in the nephron is glucose reabsorbed into the bloodstream?
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Glucose is actively transported back into the blood in the proximal tubule
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Why do our bodies need to “deaminate” amino acids?
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Removal of the amino group occurs so that proteins can be converted into carbohydrates for storage
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What is the outer part of the kidney called?
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Renal Cortex
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At approx. what volume does urine storage become painful?
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Approx. 400 mL
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What specific semi-permeable structure acts as a high pressure filter?
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The Glomerulus is a high pressure filter
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These structures carry urine from the kidneys to the bladder
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Ureters carry urine from the kidneys to the bladder.
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Where in the nephron does the majority of water reabsorption occur?
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The descending limb of the loop of Henle is the site of most water reabsorption
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Where does the majority of ACTIVE reabsorption and secretion occur in the nephron?
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The majority of ACTIVE reabsorption and secretion occurs in the proximal and distal tubules
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During osmosis, water moves from an area of _____ solute concentration (hypotonic) to an area of _____ solute concentration (hypertonic).
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Water will move from a hypotonic solution (low solute) to hypertonic (high solute)
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Name three wastes products removed by the Kidney
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Ammonia - Urea - Uric Acid - H+
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Name three substances that are actively reabsorbed back into the bloodstream
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Na+, Glucose, Amino Acids, Vitamins, other nutrients are all actively transported back into the bloodstream
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What area of the nephron has the highest mitocondria concentration and why?
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Proximal and distal tubules have lots of mitochondria due to the amount of active transport that takes place
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The word “diabetes” comes from a latin word meaning…
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… increased urine output
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Why does somebody with diabetes mellitus have increased urine output?
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Diabetes mellitus = higher blood glucose thus glucose “spills over” into urine drawing water with it.
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What is hemodialysis?
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“artificial kidney” - blood is pumped through a dialysis machine that removes wastes from the blood for somebody with a damaged kidney
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What is Diabetes Insipidus?
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Diabetes insipidus is a malfunction of ADH causing decreased water reabsorption
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When & why would somebody undergo peritoneal dialysis and why?
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When their kidney / kidney’s are not functioning but and require / request more flexibility
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How many people have won the $1 million “Deal or No Deal” prize?
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0 - Nobody has picked the right case yet.
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Explain the effect of Antidiuretic Hormone (ADH)
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ADH increases water reabsorption
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What size cube has a the largest surface area to volume ratio: 1cm, 10cm, or 1m
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The 1cm cube has the largest surface area to volume ratio - an important concept in Biology
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What type of food and/or drink is allowed in the classrooms at MCHS?
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WATER ONLY! (and sometimes doughnuts if there is enough for the whole class)
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How is aldosterone different than ADH (antidiuretic hormone)?
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Aldosterone and ADH increase water reaborption, but aldosterone does so indirectly through the reabsorption of Na+ (sodium)
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