1. NORMAL LOW T3 LOW T3-T4 LOW T3 NORMAL
TSH
rT3
Normal
Range
TT4 T3
WELL ILLNESS RECOVERY WELL
Severity Early Late

2. High rT3 Low T3 Low T4 CYTOKINES NUTRITION Local Tissue
Thyroid Hormone
Metabolism
High rT Low T Low T4
rT T2 T T Inhibitor
T T3S WBC
T T3AC X

3. HEALTHY/OUTPATIENT HOSPITALIZED/NTI
1000
1000
100
r = r = 0.22
100 10 10
TSH
TSH 1 1
0.1
0.1
FREE T FREE T4

4. WELL ILLNESS RECOVERY WELL
NORMAL LOW T3 LOW T3/T4 LOW T3 NORMAL
NORMAL
RANGE
WELL ILLNESS RECOVERY WELL
SEVERITY EARLY LATE

5. TSH < 0.4 mU/L 7.5% TSH < 0.1 TSH < 0.01 6.9% 0.6%
6.9% %
ILLNESS THYROID GLUCOCORTICOID

6. TSH > 4.5 mU/L 7.5% TSH 4.5 - 20 TSH > 20 5.8% 1.7%
5.8% %
ILLNESS THYROID