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Types of Complex Inheritance
Incomplete Dominance Codominance Multiple Alleles Polygenic Traits
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Incomplete dominance Both alleles partially show by blending together
Analogy: Mixing Together Paint Blue Green Yellow
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Both alleles are completely expressed at the same time.
codominance Both alleles are completely expressed at the same time. -Analogy: Mixing Together Pebbles Yellow AND Blue Yellow Blue
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Multiple alleles Having more than two alleles for a specific trait
Ex. An example is blood groups in humans. Blood type, for example, is determined by three alleles. A is codominant IA B is codominant IB O is recessive i
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Blood Types Alleles (Genotype) Blood Type (Phenotype)
AA or Ao IAIA or IAi Type A BBor Bo IBIB or IBi Type B AB only IAIB Type AB oo only ii Type O
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Polygenic Traits Traits that are determined by the interaction of multiple pairs of genes Ex: skin color, height
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Multiple Allele Traits: Blood Type
Blood type exhibits codominance and multiple alleles. The chart below shows the phenotype and genotype of blood types. Phenotype Genotype Type A AA or Ao IAIA or IAi Type B BB or Bo IBIB or IBi Type AB AB IAIB Type O oo ii Blood Type is controlled by 3 alleles: A, B, O. A & B are codominant, O is recessive.
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1. a) What are the two genotypes possible for a person who as A blood
1. a) What are the two genotypes possible for a person who as A blood? IAIA or IAi b) What genotype does a person with AB blood have? IAIB c ) What genotype does a person with O blood have? ii d) What are the two genotypes possible for a person who as B blood? IBIB or IBi
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Sex-Linked
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Which Chromosome Determines our Sex?
Introduction: A human has 23 pairs of homologous chromosomes Pairs 1-22 are called Autosomes – chromosomes not involved in determining sex Pair 23 – Sex Chromosomes
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How is Sex Determined? Sex chromosomes are X and Y Females are XX
Males are XY
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How is Sex Determined? Females can only make eggs with the X chromosome Males make sperm with the X or Y chromosome, so it is the male that determines the sex of a baby
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How is Sex Determined? 50% chance male 50% chance female
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Discovery of Sex-Linked Genes
Discovered in fruit flies (drosophila melanogaster) by Thomas Hunt Morgan
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Discovery of Sex-Linked Genes
Eye color is sex-linked in fruit flies. He discovered that alleles for eye color is carried on the X chromosome ONLY! NO ALLELES ON THE Y CHROMOSOME
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Why Fruit Flies? Easy to maintain 10 – 15 day life cycle
Many offspring produce in a short time
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Sex-Linked Traits Traits that are controlled by the sex chromosomes
Colorblindness – can’t see the difference between certain colors Hemophilia – blood does not clot properly
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Example H = Normal h = hemophilia
Important Rule: Only write the gene over the X chromosome
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Female Genotypes XHXH : Normal Female (Homozygous Dominant)
XHXh : Normal Female Carrier (Heterozygous) XhXh : Female with hemophilia (Homozygous Recessive)
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Male Genotypes XHY : normal male without hemophilia
XhY : male with hemophilia
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Sex-linked traits occur more in males than females because
Males only need one “bad” gene on the X chromosome But females need two “bad” genes on both X chromosomes
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