1. A Multisite Neurobehavioral Assessment of FASD
South Africa Site subcontract
(PI Dr Mattson)
Colleen Adnams
University of Cape Town
CIFASD Meeting, Chapel Hill, 8 January 2009

2. Mapping the Brain, the Face and Neurocognitive function in FASD
South Africa Site subcontract
(PI Dr Sowell) 2

3. Focus
Recent Progress
Planning for 2009 to meet consortium goals

4. Neurobehavioural Assessment Project
2008
Nov - funding released
Dec / Jan – hired neuropsychologist
2009
Jan – commenced translations of WISC-IV, D-KEFS, CANTAB
Standardised Afrikaans administration manual
Feb / Mar – Neuropsychologist training on neuroassessment battery
March – Neuropsychologist training in San Diego
Aim for reliability
March / April – pilot testing in Afrikaans
April – commence data collection, hire second tester

5. Face and Brain Imaging Project
2009
Jan – hire research assistant
Feb – Dr Narr (UCLA) to visit
Goals – review protocols
Test phantom data
Collect pilot data
March – pilot in tandem with neurobehavioral study
Standardised Afrikaans fMRI test administration
April – commence data collection

6. Some logistics at SA site
Large pool of well described FASD and control children
(FASER-SA Epi Phase 2, 3 and 4: >200 FASD and controls aged 7 – 18 yrs)
Subjects live in Wellington (75km from CT)
Neurobehavioral assessments will take place in Wellington
Imaging studies will take place at Stellenbosch University CUBBI Centre (50 km from Wellington)
All subjects require transport 6

7. Data Collection Goals Neurobehavioural Project :
100 FASD
100 Controls
40 Low IQ Total 240
Brain Imaging Project:
Year 1 and 2:
40 FASD
40 Controls
Repeat Year 3 and 4
40 Controls Total 160 7

8. Data collection Plan 2009 - 2011 - Dec 2009 Dec 2010 Dec 2011 60 90 40
Neurobehavior-al Assessment
Project 60 90
Imaging Project 40