1. Please make 4-person groups.

2. What is chromatography?
From Wikipedia ...
Chromatography (from Greek word for chromos for colour) is the collective term for a family of laboratory techniques for the separation of mixtures. It involves passing a mixture through a stationary phase, which separates it from other molecules in the mixture and allows it to be isolated.
Which means ...
Chromatography is the physical separation of a mixture into its individual components.
We can use chromatography to separate the components of inks and dyes, such as those found in pens, markers, clothing, and even candy shells. Chromatography can also be used to separate the colored pigments in plants or used to determine the chemical composition of many substances.

3. Examples of Chromatography
Liquid Chromatography
Used to identify unknown plant pigments & other compounds.
Paper Chromatography
Can be used to separate the components of inks, dyes, plant compounds (chlorophyll), make-up, and many other substances
Thin-Layer Chromatography
Uses thin plastic or glass trays to identify the composition of pigments, chemicals, and other unknown substances.
Gas Chromatography
Used to determine the chemical composition of unknown substances, such as the different compounds in gasoline shown by each separate peak in the graph below.

4. DO NOW: watch video and discuss with table partners What FDA category would Lance’s drugs fit into?

5. ANABOLIC STEROIDS and/or STIMULANTS but “doping” can mean many different things

6. NEED A VOLUNTEER TO READ THE WORDS IN BLUE

7. EVERYONE ELSE: Read the words in red

8. PRACTICE PATIENCE AND CONSIDER ALL PERSPECTIVES.

9. I have not yet processed re-grades for this class period yet.

10. Which plants did I plant this weekend?
Plum tree
Pecan tree
Mountain laurel
All of the above
None of the above

11. Which plants did I plant this weekend?
Plum tree
Pecan tree
Mountain laurel
All of the above
None of the above

14. discuss with partners: Do you agree that Lance Armstrong should have been stripped of his titles?

15. Discuss both questions with your LP: Should athletes be allowed to use anabolic steroids? Why or why not? Should athletes be allowed to use coffee? Why or why not?

16. CHOOSE Thriller Bad

17. THRILLER: Stand up and state the 5 drug classifications we learned last week to your LP.

18. CHOOSE A COMPLIMENT: Today will be great I’m ready to learn
Thanks in advance for helping me today
Forensics bros 4 life

19. CLASSIFY DRUGS ACCORDING TO THE FDA CLASSIFICATION SYSTEM
LEARNING OBJECTIVE
CLASSIFY DRUGS ACCORDING TO THE FDA CLASSIFICATION SYSTEM

20. I expect you to refrain from talking or asking about personal experiences involving drugs.

21. LEARNING OBJECTIVE
Identify controlled substances using laboratory procedures such as color test reactions, chromatography, and spectrophotometry.

22. AGENDA FOR TODAY
DO NOW: Lance was on steroids.
Color change test lab – read instructions
Do the lab
Clean up
Write mini lab report – TELPAS essay
Turn in

23. Color test Chromatography 3. Spectroscopy
METHODS OF DETECTING DRUGS / POISONS
Color test
Chromatography
3. Spectroscopy

24. Do athletes at Crockett sign an agreement to consent to random drug tests?

25. Should high school student athletes be required to consent to random drugs tests? SILENTLY choose: yes or no

26. No   Yes

27. Is Alex in trouble? http://www.youtube.com/watch?v=TVodrjz7VRU

28. ANABOLIC STEROIDS STIMULANTS

29. COPY DOWN ON RIGHT PAGE:
Just get it started; we’ll come back to this in about 5 minutes
PAPER CHROMATOGRAPHY:
MARKERS CHOSEN:
What colors did it separate into?

30. What is chromatography?
From Wikipedia ...
Chromatography (from Greek word for chromos for colour) is the collective term for a family of laboratory techniques for the separation of mixtures. It involves passing a mixture through a stationary phase, which separates it from other molecules in the mixture and allows it to be isolated.
Which means ...
Chromatography is the physical separation of a mixture into its individual components.
We can use chromatography to separate the components of inks and dyes, such as those found in pens, markers, clothing, and even candy shells. Chromatography can also be used to separate the colored pigments in plants or used to determine the chemical composition of many substances.

31. Examples of Chromatography
Liquid Chromatography
Used to identify unknown plant pigments & other compounds.
Paper Chromatography
Can be used to separate the components of inks, dyes, plant compounds (chlorophyll), make-up, and many other substances
Thin-Layer Chromatography
Uses thin plastic or glass trays to identify the composition of pigments, chemicals, and other unknown substances.
Gas Chromatography
Used to determine the chemical composition of unknown substances, such as the different compounds in gasoline shown by each separate peak in the graph below.

32. LEFT PAGE REFLECTION
Fill in your chart, and explain what happened to the ink on your LEFT PAGE.
PAPER CHROMATOGRAPHY:
MARKERS CHOSEN:
What colors did it separate into?

33. LEFT PAGE REFLECTION
What limitations to you perceive in chromatography?
Would you convict someone just based on a chromatography? Why or why not?

34. YOU WILL PERFORM A COLOR CHANGE TEST TO DETERMINE WHICH SUBSTANCE(s) MAY CONTAIN POISON.

35. Lab: Read it now please.

36. Presumptive Color Change Tests for poisons and intoxicants….
Marquis test – opium and derivatives
Duquenois-Levine test – Marijuana (THC)
Van Urk test - LSD
Scott test - Cocaine
Dillie-Koppanyi test – Barbituates
*** These are all color changing tests for detection.

37. LEFT PAGE REFLECTION
COLOR TESTS WORK LIKE THIS: 1) Mix some chemicals together. 2) Eventually, your mixture will either turn a certain color or not.
What limitations do you perceive in color change tests?
Would you convict someone just based on a color test? Why or why not?

38. spectrophotometry
Spectrophotometry (aka spectroscopy) is a way to identify substances by exposing them to electromagnetic radiation (light)

39. Learning objective
Explain the DEA’s / Controlled Substances Act’s drug scheduling system.

40. Drug Control Laws
There are varying levels and penalties based on manufacture, distribution, possession, or use of a drug, as well as the drug’s weight, type, and concentration
The Controlled Substances Act – the federal law that establishes five classifications of controlled dangerous substances on the basis of a drug’s potential abuse, potential for physical and psychological dependence, and medical value; the U.S. Attorney General has the authority to add, delete, or reschedule a drug as needed

41. Drug Control Laws (continued)
Schedule I
High potential for abuse and no currently accepted medical use in the U.S.
Examples: heroin, marijuana, methaqualone, LSD

42. Drug Control Laws (continued)
Schedule II
High potential for abuse, currently accepted medical use with severe restrictions, potential for severe physiological and psychological dependence
Examples: opium and its derivatives, cocaine, methadone, PCP, most amphetamine preparations, most barbiturate preparations, and dronabinol (the synthetic equivalent of marijuana, prescribed for medical use)

43. Drug Control Laws (continued)
Schedule III
Less potential for abuse, currently accepted medical use, potential for low to moderate physiological and high psychological dependence
All barbiturates not included in Schedule II, such as codeine preparations and anabolic steroids

44. Drug Control Laws (continued)
Schedule IV
Low potential for abuse, current medical use, limited dependence related to Schedule III
Examples: tranquilizers

45. Drug Control Laws (continued)
Schedule V
Low abuse, medical use, less potential for dependence than Schedule IV
Non-narcotic medicinal ingredients and some opiate drug mixtures

46. Drug Control Laws (continued)
Criminal Penalties Under the Act
The most severe penalties are associated with Schedule I and II
The Controlled Substance Act controls substances such as analogs and designer drugs that are chemically similar or related to controlled substances
Regulates the manufacture and distribution of precursors which are the chemical compounds used by clandestine labs to synthesize drugs

47. Last year: Me, Merlin, and Genevieve

48. DISCUSS WITH YOUR TABLE:
Why do you think we have drug laws?

49. Choose your own learning partners
Choose your own learning partners! or less people per table - Sit at a regular table, not a lab table DO NOW: 2 minutes to discuss with your table A man is returning from Oklahoma by train. He was in a train car where smoking was allowed. If he had been in a non-smoking car, he would have died. WHY?

50. An Answer: The man used to be blind -- he's returning from an eye operation which restored his sight. He spent all his money on the operation, so when the train (which had no internal lighting) goes through a tunnel, he thinks he's gone blind again and decides to kill himself. But before he could do it, he saw the light of the cigarettes people were smoking and realized he could still see.