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Increased turnover of collagen in abdominal aortic aneurysms, demonstrated by measuring the concentration of the aminoterminal propeptide of type III.

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Presentation on theme: "Increased turnover of collagen in abdominal aortic aneurysms, demonstrated by measuring the concentration of the aminoterminal propeptide of type III."— Presentation transcript:

1 Increased turnover of collagen in abdominal aortic aneurysms, demonstrated by measuring the concentration of the aminoterminal propeptide of type III procollagen in peripheral and aortal blood samples  Jari Satta, MD, Tatu Juvonen, MD, PhD, Kari Haukipuro, MD, PhD, Minna Juvonen, MD, PhD, Matti I. Kairaluoma, MD, PhD  Journal of Vascular Surgery  Volume 22, Issue 2, Pages (August 1995) DOI: /S (95) Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

2 Fig. 1 Concentration of PIIINP in peripheral venous blood of patients with AAA and two groups of control subjects (FDD, AOD); mean, standard error of mean, and 95% confidence intervals of mean are shown. For statistical comparison, one-way analysis of variance was used. Asterisk denotes p < 0.05, and four asterisks denote p < Journal of Vascular Surgery  , DOI: ( /S (95) ) Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

3 Fig. 2 Correlations between age of patient and serum PIIINP concentration in patients with AAA, control subjects with FDD and control subjects with AOD. Pearson product moment correlation coefficient, regression line with 95% confidence limits. Journal of Vascular Surgery  , DOI: ( /S (95) ) Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

4 Fig. 2 Correlations between age of patient and serum PIIINP concentration in patients with AAA, control subjects with FDD and control subjects with AOD. Pearson product moment correlation coefficient, regression line with 95% confidence limits. Journal of Vascular Surgery  , DOI: ( /S (95) ) Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

5 Fig. 2 Correlations between age of patient and serum PIIINP concentration in patients with AAA, control subjects with FDD and control subjects with AOD. Pearson product moment correlation coefficient, regression line with 95% confidence limits. Journal of Vascular Surgery  , DOI: ( /S (95) ) Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

6 Fig. 3 Correlation between serum PIIINP concentration and diameter of aneurysm in 87 patients with AAA. Pearson product moment correlation coefficient was used. Journal of Vascular Surgery  , DOI: ( /S (95) ) Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

7 Fig. 4 Correlation between serum PIIINP concentration and thickness of intraluminal thrombus in 87 patients with AAA. Pearson product moment correlation coefficient was used. Journal of Vascular Surgery  , DOI: ( /S (95) ) Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

8 Fig. 5 PIIINP concentrations in aorta above and below aneurysm in patients with AAA (A) and at diaphragm and iliac levels in aorta in patients with AOD (B) in 13 age- and sex-matched pairs. Horizontal lines in A denote median above (continuous line) and below (broken line) aneurysm. Median concentrations at diaphragm and iliac levels in AOD group (B) were equal (continuous line);z = 3.1, p = 0.002, Wilcoxon matched pairs test, for difference of gradient between groups. Journal of Vascular Surgery  , DOI: ( /S (95) ) Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

9 Fig. 5 PIIINP concentrations in aorta above and below aneurysm in patients with AAA (A) and at diaphragm and iliac levels in aorta in patients with AOD (B) in 13 age- and sex-matched pairs. Horizontal lines in A denote median above (continuous line) and below (broken line) aneurysm. Median concentrations at diaphragm and iliac levels in AOD group (B) were equal (continuous line);z = 3.1, p = 0.002, Wilcoxon matched pairs test, for difference of gradient between groups. Journal of Vascular Surgery  , DOI: ( /S (95) ) Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

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