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Is There a Role for a Collagen Conduit and Anti-Inflammatory Agent in the Management of Partial Peripheral Nerve Injuries?  Rabie M. Shanti, DMD, MD,

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Presentation on theme: "Is There a Role for a Collagen Conduit and Anti-Inflammatory Agent in the Management of Partial Peripheral Nerve Injuries?  Rabie M. Shanti, DMD, MD,"— Presentation transcript:

1 Is There a Role for a Collagen Conduit and Anti-Inflammatory Agent in the Management of Partial Peripheral Nerve Injuries?  Rabie M. Shanti, DMD, MD, Junad Khan, BDS, MDS, MPH, Eli Eliav, DMD, MSc, PhD, Vincent B. Ziccardi, DDS, MD  Journal of Oral and Maxillofacial Surgery  Volume 71, Issue 6, Pages (June 2013) DOI: /j.joms Copyright © 2013 American Association of Oral and Maxillofacial Surgeons Terms and Conditions

2 Figure 1 A, Sciatic nerve exposed and separated from the adjacent structures. B, Sciatic chronic constriction injury demonstrating the exposed sciatic nerve and loosely placed ligatures around the nerve. C, NeuraGen conduit covering sciatic nerve. Shanti et al. Management of Partial Peripheral Nerve Injuries. J Oral Maxillofac Surg 2013. Journal of Oral and Maxillofacial Surgery  , DOI: ( /j.joms ) Copyright © 2013 American Association of Oral and Maxillofacial Surgeons Terms and Conditions

3 Figure 2 Tactile allodynia measurements. BL, baseline.
Shanti et al. Management of Partial Peripheral Nerve Injuries. J Oral Maxillofac Surg 2013. Journal of Oral and Maxillofacial Surgery  , DOI: ( /j.joms ) Copyright © 2013 American Association of Oral and Maxillofacial Surgeons Terms and Conditions

4 Figure 3 Thermal withdrawal latency. BL, basline; CCI, chronic constrictive injury; CT, collagen tubule. Shanti et al. Management of Partial Peripheral Nerve Injuries. J Oral Maxillofac Surg 2013. Journal of Oral and Maxillofacial Surgery  , DOI: ( /j.joms ) Copyright © 2013 American Association of Oral and Maxillofacial Surgeons Terms and Conditions

5 Figure 4 Scanning electron micrographs of transverse cross sections of nerve samples at ×4,000 magnification. (A) Group 1—CCI. (B) Group 2—CCI and type I collagen tube. (C) Group 3—CCI and type I collagen tube soaked with anti-inflammatory agent. Shanti et al. Management of Partial Peripheral Nerve Injuries. J Oral Maxillofac Surg 2013. Journal of Oral and Maxillofacial Surgery  , DOI: ( /j.joms ) Copyright © 2013 American Association of Oral and Maxillofacial Surgeons Terms and Conditions

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