1. BIOELECTRONICS 1 Dr. Eng. Hani Kasban Mahmoud
6 October University
Faculty of Applied Medical Sciences
Department of Biomedical equipment and systems
Lec1: Introduction to Bioelectronics By
Dr. Eng. Hani Kasban Mahmoud
2017
BIOELECTRONICS 1

2. Introduction to Bioelectronics
CHAPTER 1
Introduction to Bioelectronics
Author : Dr. Eng. Hani Kasban A. Mahmoud / 2017

3. Introduction to Bioelectronics
Bioelectronics means the integration of biology with electronic elements for building higher-level functional devices.
Author : Dr. Eng. Hani Kasban A. Mahmoud / 2017

4. Introduction to Bioelectronics Measured biomaterials
Revision (Biology)
Measured biomaterials
Cells
Cells are the basic building blocks of all living things.
Proteins
Proteins are one of the building blocks of body tissue, and can also serve as a fuel source.
Enzymes
Large molecules that speed up the chemical reactions inside cells. type of protein,
Author : Dr. Eng. Hani Kasban A. Mahmoud / 2017

5. Introduction to Bioelectronics Measured biomaterials
Revision (Biology)
Measured biomaterials
Deoxyribonucleic Acid (DNA)

6. Introduction to Bioelectronics Measured biomaterials
Revision (Biology)
Measured biomaterials
The neuron (nerve cell) is the fundamental unit of the nervous system. The basic purpose of a neuron is to receive incoming information and, based upon that information, send a signal to other neurons, muscles, or glands. Neurons are designed to rapidly send signals across physiologically long distances. They do this using electrical signals called nerve impulses or action potentials .

7. Introduction to Bioelectronics Measured biomaterials
Revision (Biology)
Measured biomaterials
Receptor
Receptor is a protein-molecule that receives chemical-signals from outside a cell. When such chemical-signals bind to a receptor, they cause some form of cellular/tissue-response
Author : Dr. Eng. Hani Kasban A. Mahmoud / 2017

8. Introduction to Bioelectronics Revision (Electronics)
Electronic-Components
Author : Dr. Eng. Hani Kasban A. Mahmoud / 2017

9. Introduction to Bioelectronics Revision (Electronics)
Measured Quantities
Series
Parallel
Current
Voltage
VS = V1 + V2 + V3
VS = V1 = V2 = V3
Resistance
RS = R1+ R2 + R3
Power
PS = P1 + P2 + P3
Author : Dr. Eng. Hani Kasban A. Mahmoud / 2017

10. Equivalent circuit for describing the electrostatic interference.
Author : Dr. Eng. Hani Kasban A. Mahmoud / 2017

11. Introduction to Bioelectronics
Bioelectronic system required the existence of electronic coupling and communication between the biomolecules and the electronic supports.
Author : Dr. Eng. Hani Kasban A. Mahmoud / 2017

12. Introduction to Bioelectronics
For example, the intercalation of doxorubicin (2) into the double-stranded DNA formed between a primer nucleic acid associated with an electrode.
Author : Dr. Eng. Hani Kasban A. Mahmoud / 2017

13. Bielectronic system
Author : Dr. Eng. Hani Kasban A. Mahmoud / 2017

14. Bioelectronics Applications
Biomedical instrumentation (traditional and innovative) based on acquisition (sensors), amplification (circuits) and processing (systems) of electrical signals with biological origin.
Imaging systems for medical diagnostic employ detectors (solid state), integrated circuits (VLSI) and processing systems (ex. DSP) for the acquisition and the processing of large quantities of information
Advanced and multi-disciplinary applications of combined electronics and biology/medicine (bio-labs on chip, acquisition/stimulus of cellular electrical signals, electronics prosthesis).
Author : Dr. Eng. Hani Kasban A. Mahmoud / 2017

15. Bioelectronics Applications
Author : Dr. Eng. Hani Kasban A. Mahmoud / 2017

16. Biopotential
Biopotential is the voltage produced by the tissue of the body, particularly muscle tissue during a contraction. Electrocardiography depends on measurement of changing potentials in contracting heart muscle. Electromyography and electroencephalography function similarly in the diagnosis of neuromuscular and brain disorders, respectively.
Author : Dr. Eng. Hani Kasban A. Mahmoud / 2017

17. Biopotential Electrodes
Biopotential electrode is the transducer interface between the body and the readout circuit that converts the ionic current into electronic current, or vice versa.
Author : Dr. Eng. Hani Kasban A. Mahmoud / 2017

18. Biopotential Electrodes Equivalent Circuit
CA and RA represents the impedance associated with the electrode–electrolyte interface, and RS is the resistance of the electrolyte solution. The half-cell potential of the interface is represented with a voltage source, Vhc.
Author : Dr. Eng. Hani Kasban A. Mahmoud / 2017

19. Many thanks
Dr. Eng. Hani Kasban
Questions?????