1. Summary of the gross and microscopic changes in cardiac hypertrophy
Summary of the gross and microscopic changes in cardiac hypertrophy. (A) Gross photo of heart with hypertrophy caused by aortic stenosis. The wall of the left ventricle is thick and the chamber is not dilated. The left ventricle is on the lower right in this apical four-chamber view of the heart. (B) Altered cardiac configuration in left ventricular hypertrophy without and with dilation, viewed in transverse heart sections. Compared with a normal heart (center of this panel), a pressure overloaded heart, caused for example by aortic valve stenosis (left in [B]), has increased mass and a thick left ventricular wall, whereas a volume overloaded heart, caused for example by mitral valve regurgitation, is both hypertrophied and dilated (right), having increased mass with a near normal or diminished wall thickness. (C) Photomicrograph of normal myocardium. (D) Photomicrograph of hypertrophied myocardium, showing large cells with enlarged. ([B] Reproduced with permission from Edwards WD: Cardiac anatomy and examination of cardiac specimens, in Emmanouilides GC, Riemenschneider TA, Allen HD, et al [eds]: Moss and Adams Heart Disease in Infants, Children, and Adolescents: Including the Fetus and Young Adults, 5th ed. Philadelphia, Williams & Wilkins, 1995; p 86. [C and D] Reproduced with permission from Schoen FJ, Mitchell RN: The heart, in Kumar V, Fausto N, Abbas A, et al [eds]: Robbins/Cotran Pathologic Basis of Disease, 8th ed. Philadelphia, WB Saunders, 2010; pp )
Source: Chapter 5. Cardiovascular Pathology, Cardiac Surgery in the Adult, 4e
Citation: Cohn LH. Cardiac Surgery in the Adult, 4e; 2012 Available at: Accessed: October 08, 2017
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