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Poor glycemic control and decreased renal function are associated with increased intrarenal RAS activity in Type 2 diabetes mellitus  S. Nakatani, E.

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Presentation on theme: "Poor glycemic control and decreased renal function are associated with increased intrarenal RAS activity in Type 2 diabetes mellitus  S. Nakatani, E."— Presentation transcript:

1 Poor glycemic control and decreased renal function are associated with increased intrarenal RAS activity in Type 2 diabetes mellitus  S. Nakatani, E. Ishimura, T. Naganuma, A. Nakatani, M. Ichii, S. Fukumoto, K. Mori, M. Emoto, T. Nakatani, M. Inaba  Diabetes Research and Clinical Practice  Volume 105, Issue 1, Pages (July 2014) DOI: /j.diabres Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

2 Fig. 1 Investigation of Log (urinary [angiotensinogen:creatinine]) (Log(UAGT/Ucre)) in patients with type 2 diabetes mellitus without nephropathy. Age, hemoglobin A1c (HbA1c), and fasting plasma glucose (FPG) correlated significantly and positively with Log (UAGT/Ucre) ((A)–(C), respectively). Diabetes Research and Clinical Practice  , 40-46DOI: ( /j.diabres ) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

3 Fig. 2 Investigation of Log(urinary [angiotensinogen:creatinine]) (Log(UAGT/Ucre)) in patients with type 2 diabetes mellitus and chronic kidney disease. Systolic blood pressure (SBP), serum creatinine, and urinary [albumin:creatinine] (UACR) correlated significantly and positively with Log (UAGT/Ucre) ((A)–(C), respectively). Estimated glomerular filtration rate (eGFR) correlated significantly and inversely with the Log (UAGT/Ucre) (D). Diabetes Research and Clinical Practice  , 40-46DOI: ( /j.diabres ) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions


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