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*Author : dr Milenko Stanić

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1 Surgery of intracranial epidermoid cyst (cholesteatoma): An expirience of 15 cases
*Author : dr Milenko Stanić Coauthor : dr R. Vujović , dr M. Spaić , dr R. Benović , dr M. Marković , Dr M. Samardžić , dr I. Popović Institution: Department of Neurosurgery, Clinical center Zemun, Belgrade, Serbia

2 Introduction Intracranial epidermoid cyst are benign lesions representing 1% of all intracranial tumors , developed from ectodermal inclusion. These cysts are potentially curable that are sometimes assosiated with perioperative complications and tend to recur if not completely removed.

3 Aim To report our experience in surgery of intracranial epidermoid cyst regarding the localization of the tumor, surgical managment strategy with completeness of excision, duration of symptoms and postoperative complication.

4 Materials and Methods This study retrospectively evaluated on 15 cases of intracranial epidermoid cyst treated between January 2000 to June 2013 at the Department of Neurosurgery Clinical center Zemun follow-up was at least six months

5 Materials and Methods Analysis patient according to: Sex & age
Localisation Degree of resection Duration of symptoms Postoperative complication

6 Results There were nine male and six female in the series. The average age was 42,6 years . Common clinical presentations included : headache, cerebellar dysfunction, cranial nerve impairment, and seizures. The duration of the disease at admission varied between fifth months to four years.

7 Results Nine (60%) patients were infartentorial , fifth patients were (33,3%) supratentorial and one patient was supra and infratentorial localization.

8 Results The resection was total in seven (46,6%) cases and subtotal in eight (53,4%) of cases . Post-operative aseptic/chemical meningitis developed four patients (26.7%) and deterioration of neurological deficit three (20%) patients. Mortality rate was 6,67%.

9 Postoperative complication
Case No Age/Sex Lesion localisation Duration of symptoms Degree of resection Postoperative complication 1.J.N. 48/male CPA 2 years incomplete none 2. Z.B. 52/female parasellar 16 months aseptic meningitis 3. P.M. 63/male diploice 1 year complete 4. J.M. 25/female 5 years 5. N.S. 51/male 9 months VII et VIII cranial lesion 6.M.R. 62/male CPA&parasellar 7.Lj.Z. 46/female fourth venricle 5 months 8.Z.G. 29/male hemiparesis 9. M.J. 52/ female 3 years 10.Z.Ž. 61/female fourth ventricle 6 months 11. V.R. 45/male 12. N.K. 57/female 8 months 13. Z.M. 39/male 12 months 14. R.Z. 36/male 15.G.Z. 20 months

10 Conclusion Epidermoid cysts are characterized by a long evolution.
The diagnosis is relatively characteristic in the imagery Prognosis was favorable with a complete surgical resection.


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