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Presented By James Hill at 2016 ASCO Annual Meeting

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Presentation on theme: "Presented By James Hill at 2016 ASCO Annual Meeting"— Presentation transcript:

1 Presented By James Hill at 2016 ASCO Annual Meeting
The CREST Trial Presented By James Hill at 2016 ASCO Annual Meeting

2 Learning Objectives for obstructing colorectal cancer
Presented By James Hill at 2016 ASCO Annual Meeting

3 Rationale of CREST – Converting emergency into elective surgery
Presented By James Hill at 2016 ASCO Annual Meeting

4 Presented By James Hill at 2016 ASCO Annual Meeting
Self-expandable metal stents for obstructing colonic and extracolonic cancer: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline - Endoscopy 2014; 46: 990–1002 Presented By James Hill at 2016 ASCO Annual Meeting

5 CREST – Primary Objectives
Presented By James Hill at 2016 ASCO Annual Meeting

6 CREST – Secondary outcome measures
Presented By James Hill at 2016 ASCO Annual Meeting

7 Presented By James Hill at 2016 ASCO Annual Meeting
The CREST Trial Design Presented By James Hill at 2016 ASCO Annual Meeting

8 CREST – Eligibility Criteria
Presented By James Hill at 2016 ASCO Annual Meeting

9 Compliance with Randomised Treatment Allocation
Presented By James Hill at 2016 ASCO Annual Meeting

10 CREST Patient Demographics
Presented By James Hill at 2016 ASCO Annual Meeting

11 CREST Patient Baseline Data
Presented By James Hill at 2016 ASCO Annual Meeting

12 CREST Patient Baseline Data - Stratification
Presented By James Hill at 2016 ASCO Annual Meeting

13 Does stenting reduce length of stay and 30-day mortality?
Presented By James Hill at 2016 ASCO Annual Meeting

14 Stenting Completion and Immediate Complication Rate
Presented By James Hill at 2016 ASCO Annual Meeting

15 Stenting Intermediate and Late Complication Rates
Presented By James Hill at 2016 ASCO Annual Meeting

16 Stent related perforations
Presented By James Hill at 2016 ASCO Annual Meeting

17 Does stenting reduce stoma rates?
Presented By James Hill at 2016 ASCO Annual Meeting

18 Presented By James Hill at 2016 ASCO Annual Meeting
6-Month Survival Rates Presented By James Hill at 2016 ASCO Annual Meeting

19 Severity of Surgical Complications (Clavien-Dindo Classification)
Presented By James Hill at 2016 ASCO Annual Meeting

20 Presented By James Hill at 2016 ASCO Annual Meeting
Summary Presented By James Hill at 2016 ASCO Annual Meeting

21 Conclusions – SEMS as a bridge to surgery
Presented By James Hill at 2016 ASCO Annual Meeting


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