1. APPLICATIONS OF CYTOTOXICITY

2. Index What is Cytotoxicity ( introduction) Applications :-
Testing Pharmaceuticals
Anticancer Drug Screening
Predictive Drug Testing For Tumors

3. What is Cytotoxicity ?
Cytotoxicity is the degree to which an agent has specific destructive action on certain cells
The possession of such destructive action, particularly in reference to lysis of cells by immune phenomena and to antineoplastic agents that selectively kill dividing cells.

4. Application of Cytotoxicity
TESTING PHARMACEUTICALS
In vitro testing of drugs on animals is expensive .
This animal drug testing is ethically non-acceptable.
The animals testing of drugs is difficult to introduce as complexity of wide range of effects seen in vivo.
But with Cytotoxicity assay, researchers can look for Cytotoxic compounds that targets rapidly dividing cancer cells.

5. ANTICANCER DRUG SCREENING
In this the drug screening and dosage is checked
In this cutting down on manipulations the MTT(methyl tetrazolium) incubation step and the point determined by measuring the amount of total protein with sulforhodamine B may be omitted.
This method is easier and quicker then the MTT assay.

7. PREDICTIVE DRUG TESTING FOR TUMORS In this the testing of predictive drug designs are done which can localize the tumor.

8. Thank You