1. Volume 178, Issue 3, Pages 1080-1085 (September 2007)
Prostate Tissue Analysis Immediately Following Magnetic Resonance Imaging Guided Transurethral Ultrasound Thermal Therapy 
Aaron Boyes, Kee Tang, Martin Yaffe, Linda Sugar, Rajiv Chopra, Michael Bronskill 
The Journal of Urology 
Volume 178, Issue 3, Pages (September 2007)
DOI: /j.juro
Copyright © 2007 American Urological Association Terms and Conditions

2. Fig. 1
Schematic transaxial cross-section of prostate shows sectors of thermal coagulation generated at constant rotation rates. Extents of sectors 1 and 2 were varied by adjusting mechanical rotation rate based on numerical simulation results.
The Journal of Urology  , DOI: ( /j.juro )
Copyright © 2007 American Urological Association Terms and Conditions

3. Fig. 2 Schematic of apparatus used to section fresh tissue
The Journal of Urology  , DOI: ( /j.juro )
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4. Fig. 3
A, transurethral ultrasound heating applicator. B, MRI shows transducer position before thermal treatment. C, CE MRI studies stacked to visualize slice thickness, scaled to B and ruler. Transducer center is aligned by MRI coordinates in B and C corresponding to white line in C near 2 mm mark.
The Journal of Urology  , DOI: ( /j.juro )
Copyright © 2007 American Urological Association Terms and Conditions

5. Fig. 4
A, CE MRI acquired approximately 30 minutes after treatment. Urethral opening was maintained by heating applicator. B, unstained prostate section. C, prostate section after TTC assay. B and C, urethral opening was maintained by plastic rod.
The Journal of Urology  , DOI: ( /j.juro )
Copyright © 2007 American Urological Association Terms and Conditions

6. Fig. 5
A, whole mount 5 μm section of canine prostate stained with H&E. Graphic indicates device position in urethra and rotation direction. Rectangle indicates area of B. B, thermal damage boundaries. C to F, details of areas in B. C, TFZ. D, CNZ. E, MZ. F, UZ.
The Journal of Urology  , DOI: ( /j.juro )
Copyright © 2007 American Urological Association Terms and Conditions

7. Fig. 6
A, altered MZ appearance near blood vessels. B, magnified image shows hemostasis in CNZ. Vessel segments in plane of this section demonstrated blood coagulated in situ. Arrows indicate vessel lumina visible in heating pattern.
The Journal of Urology  , DOI: ( /j.juro )
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8. Fig. 7
Correlation of features on H&E stained and fresh tissue sections. A, polar graph shows 3 thermal damage zones on H&E micrographs. In this treatment 1 continuous sector was treated over range of angles indicated. B, radial distance of hemorrhagic band, inner boundary of TTC viability, MZ and CE nonenhancing region over sector treated in A.
The Journal of Urology  , DOI: ( /j.juro )
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