1. Chronic Fatigue Syndrome (CFS) and Cancer Related Fatigue (CRF): two “fatigue” syndromes with overlapping symptoms and possibly related aetiologies 
Ugo Rovigatti 
Neuromuscular Disorders 
Volume 22, Pages S235-S241 (December 2012)
DOI: /j.nmd
Copyright © 2012 Elsevier B.V. Terms and Conditions

2. Fig. 1
(A) Logical inference for virus presence in PCa: at the 2010 Meeting on Muscle Fatigue, we presented a logical inference analysis of the different steps involved in “Silverman journey” toward identification of the HPC-1 locus. Among all different steps, the one with highest likelihood of an error was the viro-chip detection of XMRV. (B) Time-line Of XMRV discovery and dismissal: the most relevant findings are reported in a “time-line” representation for both XMRV discovery and its dismissal after further experimentations. The data presented here refer to the period 2006–2012 and according to Refs. [5–7].
Neuromuscular Disorders  , S235-S241DOI: ( /j.nmd )
Copyright © 2012 Elsevier B.V. Terms and Conditions

3. Fig. 2
MFV properties and association with CFS/CRF. (A) Micro-Foci of N-cells growing on mesenchimal monolayers of S-cells. They are shown at lower (50×) and higher (200×) magnifications. (B) Micro-Foci Inducing Virus detected by Transmission Electron Microscopy (TEM) after positive (left) and negative staining (right). Magnifications are 8000 and 110,000 respectively. (C) Normal mock infected neuroblasts (SK-N-SH), mostly S-cells. Magnification=200×. (D) Normal neuroblasts (SK-N-SH) two weeks after infection by MFV, displaying extensive transfomation in vitro (magn. 200×). (E) MYCN amplification induction in two cell lines (SK-N-AS and VA-N-BR) initially diploid for MYCN. Amplification levels are valuated in the order of 100×. (F) MYCN amplification in neuroblasts SK-N-SH presented in Fig. 2D, measured by Q-PCR: amplification level is approximately 15×. (G) 106 Cells presented/described in Figs. 2D and F were injected into the left flank of nude mice. As Controls, the same number of mock-infected cells were injected into the counter-lateral right flank. (H) As presented at the July 2010 Muscle Fatigue Meeting, a list of features which better associate MFV to Chronic Fatigue Syndrome and Cancer Related Fatigue (as compared to XMRV).
Neuromuscular Disorders  , S235-S241DOI: ( /j.nmd )
Copyright © 2012 Elsevier B.V. Terms and Conditions