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HPTN Modelling Centre symposium “Recent advances in mathematical modelling to inform HIV prevention research activities and directions” IAS 2017 in.

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Presentation on theme: "HPTN Modelling Centre symposium “Recent advances in mathematical modelling to inform HIV prevention research activities and directions” IAS 2017 in."— Presentation transcript:

1 HPTN Modelling Centre symposium “Recent advances in mathematical modelling to inform HIV prevention research activities and directions” IAS 2017 in Paris Tuesday 25 July: 18:30 -20:30

2 The HPTN aims to develop new biomedical HIV prevention tools and improve the use of existing ones worldwide through integrated strategies, particularly for populations: Men who have sex with men (MSM) Women at high risk Adolescent at risk Substance users

3 HTPN groups and Committees
Marie-Claude Boily (Lead) Kate Mitchell Tim Hallett Christophe Fraser Marie-Claude Boily Kate Mitchell Tim Hallett Christophe Fraser Dobromir Dimitrov

4 Our Role Provide modelling support to HPTN research activities at different stages of trial development & inform research directions Before During After

5 Our Role Provide modelling support to HPTN research activities
Inform trials Inform the design, conduct, interim and final analysis of clinical trials Assess the population-level impact of the roll-out of the HIV intervention – tested in trials Research directions Understand the transmission dynamics and key epidemic drivers of the HIV epidemic – who and what risk behaviour to focus on Conduct innovative modelling work to explore new lines of investigation Conduct methodological work to improve mathematical models and study designs. Dimitrov Prevost Mitchell

6 Our Role Provide modelling support to HPTN research activities
Inform trials Inform the design, conduct, interim and final analysis of clinical trials Assess the population-level impact of the roll-out of the HIV intervention – tested in trials Research directions Understand the transmission dynamics and key epidemic drivers of the HIV epidemic – who and what risk behaviour to focus on Conduct innovative modelling work to explore new lines of investigation Conduct methodological work to improve mathematical models and study designs. Dimitrov Prevost Mitchell Vickerman Maheu-Giroux Martin

7 HPTN Modelling Centre symposium Recent advances in mathematical modelling to inform HIV prevention research activities and directions” 18:30 Introduction to HPTN Modelling Centre Marie-Claude Boily, Imperial College London, United Kingdom 18:35 Estimating the contribution of key populations towards sexual HIV transmission in Senegal Peter Vickerman, University of Bristol, United Kingdom 18:55 Women at risk, young people and HIV interventions in Ivory Coast: what is their impact on the national HIV epidemic? Mathieu Maheu-Giroux, McGill University, Canada 19:15 Estimating the impact of improvements in the HIV care cascade on HIV incidence among men who have sex with men in the US: mathematical modelling for HPTN 078 Kate Margaret Mitchell, Imperial College London, United Kingdom 19:35 Recruitment of Female Sex Workers in HIV Prevention Trials: Could Efficacy Endpoints Be Reached More Efficiently in HPTN trials? Dobromir Dimitrov, Fred Hutchinson Cancer Research Center, United States 19:50 An efficient individual based model for the HPTN 071 (PopART) cluster randomised trial: design, implementation and application William Probert, University of Oxford, United Kingdom 20:10 Estimating the contribution of prison and impact of incarceration-related interventions on HIV and HCV epidemics among PWID Nathasha Martin, University of California San Diego, United State

8 Our Role Provide modelling support to HPTN research activities
Inform trials Inform the design, conduct, interim and final analysis of clinical trials Assess the population-level impact of the HIV intervention – tested in trials Research directions Understand the transmission dynamics and key epidemic drivers of the HIV epidemic – who and what risk behaviour to focus on Conduct innovative modelling work to explore new lines of investigation Conduct methodological work to improve mathematical models and study designs. Before During After Dimitrov Prevost Mitchell Vickerman Maheu-Giroux Martin

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