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Published byEunice Walsh Modified over 6 years ago
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Triple-Negative and BRCA-Mutated Metastatic Breast Cancer
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TNBC Overview
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TNBC Subtypes
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Case Overview
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Recommended Regimens for the First-Line Treatment of MBC
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TNT Study: Carboplatin vs Docetaxel in Advanced TNBC or BRCA1/2-Positive MBC
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tnAcity: Phase 2 Trial of Nab-Paclitaxel and Carboplatin in Front-Line Metastatic TNBC
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Androgen Signaling and TNBC
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Targeting the AR Pathway in TNBC Bicalutamide
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Phase 2 Single-Arm Study of Bicalutamide in AR-Positive, ER-Negative MBC
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Targeting the AR Pathway in TNBC Enzalutamide
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Phase 2 Study of Enzalutamide in Advanced AR-Positive TNBC
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ENDEAR: Phase 3 Trial of Enzalutamide-Positive Paclitaxel in Advanced Diagnostic-Positive TNBC
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UCBG 12-1: Phase 2 Trial of Abiraterone Acetate-Prednisone in Advanced AR-Positive TNBC
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Phase 1b/2 Data for Pembrolizumab in Advanced TNBC
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Ongoing Studies of Immune Checkpoint Inhibitors in Advanced TNBC
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PARP Inhibitors in TNBC
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Randomized Phase 2 Trial of Veliparib and Cyclophosphamide in Advanced TNBC
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Phase 1 Trial of Olaparib and Paclitaxel in TNBC
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PARP Inhibitors in BRCA-Mutated MBC
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Phase 2 Study of Lurbinectedin in BRCA-Mutated MBC
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Antibody-Drug Conjugates in Development for TNBC
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Concluding Remarks
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