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Early Results from a United States Trial of Prostatic Artery Embolization in the Treatment of Benign Prostatic Hyperplasia  Sandeep Bagla, MD, Cynthia.

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Presentation on theme: "Early Results from a United States Trial of Prostatic Artery Embolization in the Treatment of Benign Prostatic Hyperplasia  Sandeep Bagla, MD, Cynthia."— Presentation transcript:

1 Early Results from a United States Trial of Prostatic Artery Embolization in the Treatment of Benign Prostatic Hyperplasia  Sandeep Bagla, MD, Cynthia P. Martin, MS, Arletta van Breda, MSN, Michael J. Sheridan, ScD, Keith M. Sterling, MD, Dimitrios Papadouris, MD, Kenneth S. Rholl, MD, John B. Smirniotopoulos, MS, Arina van Breda, MD  Journal of Vascular and Interventional Radiology  Volume 25, Issue 1, Pages (January 2014) DOI: /j.jvir Copyright © 2014 SIR Terms and Conditions

2 Figure 1 (a) Coronal T2-weighted MR image of the prostate demonstrates heterogeneous nodular enlargement of the central gland, with impingement on the bladder neck secondary to median lobe hypertrophy (black arrow). (b) Selective angiography of the left prostatic artery (white arrow) shows an enlarged prostate gland with increased vascularity in the central gland. (c) Coronal reformatted image from cone-beam CT after left prostatic artery injection depicts near-homogenous perfusion of the left hemiprostate (black asterisk), without evidence of potential nontarget embolization. (d) Angiogram after embolization to a target endpoint of near-stasis shows a lack of significant parenchymal perfusion. Journal of Vascular and Interventional Radiology  , 47-52DOI: ( /j.jvir ) Copyright © 2014 SIR Terms and Conditions

3 Figure 2 Graph of mean changes in AUA symptom score and QOL at 1 month. The 95% confidence intervals are in parentheses. Journal of Vascular and Interventional Radiology  , 47-52DOI: ( /j.jvir ) Copyright © 2014 SIR Terms and Conditions

4 Figure 3 Graph of mean changes in AUA symptom score and QOL at 3 months. The 95% confidence intervals are in parentheses. Journal of Vascular and Interventional Radiology  , 47-52DOI: ( /j.jvir ) Copyright © 2014 SIR Terms and Conditions

5 Figure 4 MR image before PAE: postcontrast subtraction imaging depicts enlarged hypervascular central prostate gland. Journal of Vascular and Interventional Radiology  , 47-52DOI: ( /j.jvir ) Copyright © 2014 SIR Terms and Conditions

6 Figure 5 MR image after PAE: postcontrast subtraction imaging demonstrates decreased enhancement in the central gland, including the periurethral area (white arrow). The gland decreased in volume by 20%. Journal of Vascular and Interventional Radiology  , 47-52DOI: ( /j.jvir ) Copyright © 2014 SIR Terms and Conditions

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