1. Factors that effect EDV and ESV
The Heart as a Pump
Cardiac Output
Cardiac Reserve
Factors that effect EDV and ESV
Be able to use the concepts of EDV, ESV and SV to determine CO.
Be able to explain the concept of cardiac reserve.
Be able to define vagal tone, bradycardia and tachycardia.
Be able to discuss how preload, contractility and afterload affect EDV. ESV and SV.
Marieb 18

2. The Heart as a Pump
Stroke Volume
Cardiac Output
Cardiac Reserve

3. The Two Circulations Volumes in R/L ventricles are equal
Volumes in the two circulations are NOT

4. Stroke Volume
End Diastolic Volume (EDV)
End Systolic Volume (ESV)

5. Cardiac Output (CO)
CO= HR x SV

6. Cardiac Reserve
COMax - CORest
= COReserve

7. Cardiac Reserve
COMax - CORest
= COReserve

8. Improving Cardiac Reserve
SVMax
HRRest

9. Resting Heart Rate Decreases from Birth
♂ 64-72
♀ 72-80

10. Tachycardia (100 or more beats/min)
Bradycardia
(60 or less
beats/min)
Miguel Indurain
A Bradycardia Sufferer

11. Heart Rate Control
Parasympathetic
(Vagal Tone)
Sympathetic
Adrenal

12. Changing Stroke Volume
Increasing/Decreasing EDV
Increasing/Decreasing ESV

13. Factors that Alter EDV and ESV
Preload
Contractility
Afterload

14. Preload: Heart “Stretchiness”
Affects EDV
Cardiac muscle stretches as heart fills

15. Frank-Starling Law of the Heart
The volume of blood ejected from a ventricle during systole (contraction) depends on the volume present in the ventricle at the end of diastole (relaxation)

16. Frank-Starling Curve

17. Venous Return and Preload
Blood returning to heart from veins
Slow heart rate
Exercise
Very fast heart rate
Blood Loss

18. Contractility increases SV
Contractile strength at a given muscle length
More Ca++
Less Ca++

19. Afterload Decreases Stroke Volume
Pressure in aorta decreases the amount of blood that can leave the left ventricle
120mmHg
80mmHg
120mmHg
100mmHg