1. P-WT-325- Corneal Topography In Childhood Glaucoma Patients
Perucho-González L, Sáenz-Francés F, Morales-Fernández L, Martínez de la Casa JM, Méndez-Hernández C,
García-Feijoó J
Hospital Clínico San Carlos, Madrid, Spain
PURPOSE
To investigated the topography and the irregular astigmatism of the cornea in eyes with childhood glaucoma (CG).
METHODS
Cross-sectional study in which 94 eyes of 55 CG patients and 66 eyes of 34 age-matched controls underwent measurements using Pentacam. Corneal topographic changes and 4th order aberrations were evaluated on Pentacam in eyes with CG and those changes were compared with the control eyes.
RESULTS
Variable
CG eyes (n94)
Control eyes (n66)
p value*
Age (years)
5.642.85
5.203.25
0.376
Anterior Max. Elevation (AME)
9.008.79
3.252.26
< 0.001
Posterior Apex Elevation (PAE)
3.1911.89
0.902.95
0.039
Posterior Max. Elevation (PME)
30.8328.21
7.588.59
Anterior Apex Elevation (AAE)
2.883.73
2.444.65
0.300
Anterior Central Elevation (ACE)
2.421.98
2.492.05
0.127
Posterior Central Elevation (PCE)
2.8115.05
1.073.15
0.057
Anterior Chamber Volume (ACV)
267.1964.82
194.2034.98
< 0.001
Anterior Chamber Depth (ACD)
3.690.64
3.140.29
Corneal astigmatism (Pmax, diopter cylinder)
40.79 3.01
44.091.74
< 0.001
However, 4th order aberrations measured by coma were statistically significantly higher in CG group compared to the values in healthy patients (Mann- Whitney test, z= -4.69, p<0.001).
CONCLUSION
We found that CG causes a significant increase in posterior maximun and apex corneal elevation; anterior maximun corneal elevation; and in anterior chamber size (both volume and depth). We also found more rate of irregular astigmatism in CG patients compared to controls.
REFERENCES
Patil B, Tandon R & Sharma N (2015): Corneal changes in childhood glaucoma. Ophthalmology 122: 87–92.