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Volume 131, Issue 5, Pages e202-e209 (May 2013)

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Presentation on theme: "Volume 131, Issue 5, Pages e202-e209 (May 2013)"— Presentation transcript:

1 Volume 131, Issue 5, Pages e202-e209 (May 2013)
Hemodialysis duration, Human platelet antigen HPA-3 and IgA Isotype of anti- β2glycoprotein I antibodies are associated with native arteriovenous fistula failure in Tunisian hemodialysis patients  Samira Hadhri, Mohamed Ben Rejeb, Anis Belarbia, Abdellatif Achour, Hadef Skouri  Thrombosis Research  Volume 131, Issue 5, Pages e202-e209 (May 2013) DOI: /j.thromres Copyright © 2013 Elsevier Ltd Terms and Conditions

2 Fig. 1 Concentrations of aCL [IgG (A), IgM (B) and IgA (C)] and anti-β2GPI [IgG (D), IgM (E) and IgA (F)] in hemodialysis patients with and without thrombosis of their vascular access. NAVFT: no arteriovenous fistula thrombosis; AVFT: arteriovenous fistula thrombosis. Dotted lines represent cut-off values (8 U/mL for anti-β2GPI isotype levels, 10 for GPL, 7 for MPL and 10 for APL). In univariate and subsequent multivariate regression analysis, differences between patients with and without AVFT were not significant, except for anti-β2GPI IgA isotype frequencies (p=0.02). Thrombosis Research  , e202-e209DOI: ( /j.thromres ) Copyright © 2013 Elsevier Ltd Terms and Conditions

3 Fig. 2 Kaplan-Meier survival curve comparing subjects positive and negative for anti-β2GPI IgA; the log-rank test indicated a significant difference (P=0.014). Thrombosis Research  , e202-e209DOI: ( /j.thromres ) Copyright © 2013 Elsevier Ltd Terms and Conditions


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