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About 10% of bone is replaced every year in an adult skeleton

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Presentation on theme: "About 10% of bone is replaced every year in an adult skeleton"— Presentation transcript:

1 About 10% of bone is replaced every year in an adult skeleton
Bone Remodeling constant balance of bone deposit and removal that occurs throughout your life bone deposit occurs at a greater rate when bone is injured bone resorption allows calcium of degraded bone matrix to move into the blood. About 10% of bone is replaced every year in an adult skeleton

2 osteoblasts osteoclasts Maintenance of Bone bone formation
bone reabsorption osteoblasts osteoclasts

3 Control of Remodeling Hormonal
 Rising blood Ca2+ levels trigger the thyroid to release calcitonin   Calcitonin stimulates calcium salt deposit in bone   Falling blood Ca2+ levels signal the parathyroid glands to release Parathyroid hormone (PTH)   PTH signals osteoclasts to degrade bone matrix and release Ca2+ into the blood 

4 Hormonal effects osteoblasts osteoclasts Calcitonin (CT) from thyroid
bone formation bone reabsorption osteoblasts osteoclasts Calcitonin (CT) from thyroid Parathyroid hormone (PTH) from parathyroid

5 Before age 25 osteoblasts osteoclasts Increase bone mass
bone formation bone reabsorption osteoblasts osteoclasts Before age 25

6 bone formation bone reabsorption osteoblasts osteoclasts Age 25-50

7 Age 50-on osteoblasts osteoclasts Decrease bone mass bone formation
bone reabsorption osteoblasts osteoclasts Age 50-on

8 Stress increases bone density
Stress effects bone formation bone reabsorption osteoblasts osteoclasts Stress increases bone density

9


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