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Published byBrice Austin Mason Modified over 6 years ago
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About 10% of bone is replaced every year in an adult skeleton
Bone Remodeling constant balance of bone deposit and removal that occurs throughout your life bone deposit occurs at a greater rate when bone is injured bone resorption allows calcium of degraded bone matrix to move into the blood. About 10% of bone is replaced every year in an adult skeleton
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osteoblasts osteoclasts Maintenance of Bone bone formation
bone reabsorption osteoblasts osteoclasts
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Control of Remodeling Hormonal
Rising blood Ca2+ levels trigger the thyroid to release calcitonin Calcitonin stimulates calcium salt deposit in bone Falling blood Ca2+ levels signal the parathyroid glands to release Parathyroid hormone (PTH) PTH signals osteoclasts to degrade bone matrix and release Ca2+ into the blood
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Hormonal effects osteoblasts osteoclasts Calcitonin (CT) from thyroid
bone formation bone reabsorption osteoblasts osteoclasts Calcitonin (CT) from thyroid Parathyroid hormone (PTH) from parathyroid
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Before age 25 osteoblasts osteoclasts Increase bone mass
bone formation bone reabsorption osteoblasts osteoclasts Before age 25
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bone formation bone reabsorption osteoblasts osteoclasts Age 25-50
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Age 50-on osteoblasts osteoclasts Decrease bone mass bone formation
bone reabsorption osteoblasts osteoclasts Age 50-on
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Stress increases bone density
Stress effects bone formation bone reabsorption osteoblasts osteoclasts Stress increases bone density
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