1. Real-time use of instantaneous wave–free ratio: Results of the ADVISE in-practice: An international, multicenter evaluation of instantaneous wave–free ratio in clinical practice 
Ricardo Petraco, MD, Rasha Al-Lamee, MBBS, Matthias Gotberg, MD, PhD, Andrew Sharp, MBBS, PhD, Farrel Hellig, MD, Sukhjinder S. Nijjer, MBChB, Mauro Echavarria-Pinto, MD, Tim P. van de Hoef, MD, Sayan Sen, MBBS PhD, Nobuhiro Tanaka, MD PhD, Eric Van Belle, MD, PhD, Waldemar Bojara, MD, Kunihiro Sakoda, MD, Martin Mates, MD, PhD, Ciro Indolfi, MD, Salvatore De Rosa, MD, PhD, Christian J. Vrints, MD, PhD, Steven Haine, MD, Hiroyoshi Yokoi, MD, Flavio L. Ribichini, MD, Martjin Meuwissen, MD, PhD, Hitoshi Matsuo, MD, PhD, Luc Janssens, MD, Ueno Katsumi, MD, Carlo Di Mario, MD, PhD, Javier Escaned, MD, PhD, Jan Piek, MD, PhD, Justin E. Davies, MBBS, PhD 
American Heart Journal 
Volume 168, Issue 5, Pages (November 2014)
DOI: /j.ahj
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2. Figure 1
Pressure normalization, temporal alignment, and iFR calculation using the hemodynamic console.
American Heart Journal  , DOI: ( /j.ahj )
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3. Figure 2 Importance of ECG detection for accurate iFR measurement.
American Heart Journal  , DOI: ( /j.ahj )
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4. Figure 3
Frequency distribution of FFR and percentage diameter stenosis values in the study.
American Heart Journal  , DOI: ( /j.ahj )
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5. Figure 4 Diagnostic agreement between iFR and FFR.
American Heart Journal  , DOI: ( /j.ahj )
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6. Figure 5
Decision-making strategies of revascularization, using iFR only (bottom panel) and a hybrid iFR-FFR approach (top panel). FFR gray zone ( ) refers to a region within which is known to be safe to defer and treat stenoses with equivalent clinical outcomes.
American Heart Journal  , DOI: ( /j.ahj )
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7. Figure 6
Screenshots of measurements of iFR and FFR. A, An example of interrogation in the left circumflex artery (horizontal arrow), in which both iFR and FFR were negative, above their respective cutoffs of 0.90 and 0.80; revascularization was deferred. B, An example in which both iFR and FFR revealed a functionally significant stenosis in the proximal segment of the left anterior descending artery (oblique arrow); percutaneous revascularization was performed. Because iFR is performed without the need for vasodilator administration, the time of lesion interrogation is typically reduced to around 5 to 10 seconds, from 60 to 120 seconds for FFR.
American Heart Journal  , DOI: ( /j.ahj )
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8. Figure 7
The FLAIR trial will evaluate the clinical merits of iFR guided revascularization.
American Heart Journal  , DOI: ( /j.ahj )
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9. American Heart Journal 2014 168, 739-748DOI: (10.1016/j.ahj.2014.06.022)
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