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GUT PHYSIOLOGY Motility-II Dr. Jack Grider Rm Sanger Hall

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Presentation on theme: "GUT PHYSIOLOGY Motility-II Dr. Jack Grider Rm Sanger Hall"— Presentation transcript:

1 GUT PHYSIOLOGY Motility-II Dr. Jack Grider Rm 12-004 Sanger Hall
2009

2 Motility: Intestine Three types of normal motility patterns in intestine Peristalsis Segmentation

3 Motility: Intestine Two types of abnormal motility patterns in intestine

4 Motility: Intestine Two types of motility patterns predominate in the postprandial intestine: peristalsis (- - -) and segmentation (▼)

5 Motility: Intestinal Peristalsis

6 Motility: Intestinal Peristalsis
Peristalsis is a 2-component short arc reflex

7 Motility: Intestinal Peristalsis
Chemical & mechanical stimulation / /Tk/NPY (IPAN) Distension mucosa (Extrinsic Afferent) GABA/GRP GABA/GRP CGRP Primary afferent orad caudad

8 Motility: Intestinal Segmentation

9 Motility: Intestinal Segmentation

10 Motility: Intestinal Segmentation

11 Phase Phase II Phase III Phase I
Motility: Intestine Interdigestive Motility Phase Phase II Phase III Phase I Myoelectrical Activity Contractile Activity

12 Motility: Intestine

13 Motility: Intestine The simple motility patterns governed by short arc reflexes and electrical activity are further modified by Long Arc Reflexes such as the Intestino-Intestinal reflex. There are many others.

14 Motility: Intestine

15 Motility:Colon

16 Motility: Colon Mass Movement Or Giant Contractions Mixing Movements
Peristaltic & Antiperistaltic

17 Motility:Defecation Reflex

18 Motility: Defecation Extracolonic muscles play an important role in defecation


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