2. Disclosure belangen NHG spreker
(Potentiële) belangenverstrengeling
Nvt
Voor bijeenkomst mogelijk relevante relaties met bedrijven
Sponsoring of onderzoeksgeld
Honorarium of andere (financiële) vergoeding
Aandeelhouder
Andere relatie, namelijk …

3. The association between social jetlag, the metabolic syndrome and type 2 diabetes mellitus in the general population: the New Hoorn study
Femke Rutters, PhD

4. Question?

5. Introduction
Circadian rhythm
Metabolism & Behavior
Jetlag, shift work

6. Introduction
Social jetlag

7. AIM
To assess the association of social jetlag with the metabolic syndrome and type 2 diabetes mellitus, in a population-based cohort.

8. Materials and Methods
New Hoorn Study Cohort

9. Materials and Methods
Poisson and linear regression

10. Results Social j <1 h Social j 1-2h Social j >2h Number (n, %)
Social j <1 h
Social j 1-2h
Social j >2h
Number (n, %)
971
497
117
Sex (men %) 46 47 59
Age (years)
64 ± 6
57 ± 5
Education level (low %) 6 3 2

11. Results Metabolic syndrome >61 y <61 y Crude Adjusted
Social j 1-2h
1.13 (0.8; 1.6)
0.86 (0.6; 1.3)
Social j > 2h
1.19 (1.3; 2.9)
0.39 (0.1; 1.5)
1.22 (0.8; 1.8)
1.04 (0.7; 1.6)
2.06 (1.3; 3.3)
0.58 (0.2; 2.2)

12. Results Pre-diabetes >61 y <61 y Crude Adjusted Social j 1-2h
1.35 (1.0; 1.8)
0.94 (0.7; 1.2)
Social j > 2h
1.79 (1.3; 2.5)
0.58 (0.3; 1.3)
1.39 (1.0; 1.9)
0.89 (0.7; 1.2)
1.73 (1.2; 2.5)
0.54 (0.3; 1.2)

13. Discussion Social jetlag, 2x higher risk Younger population
Jetlag, shift work

14. Discussion

15. Conclusion
In our population-based cohort social jetlag was associated with a 2-fold increased risk of the metabolic syndrome and (pre-)diabetes mellitus, especially in younger participants.

16. Take home message

17. Conclusion
In our population-based cohort social jetlag was associated with a 2-fold increased risk of the metabolic syndrome and (pre-)diabetes mellitus, especially in younger participants.