1. Lymphatic System Organization
What is the Overview of the Body’s Defenses?
Non-specific defenses
Protect against any threat
Specific defenses
Protect against particular threats
Responds to antigens
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2. Nonspecific Defenses Physical Barriers Skin, hair, & skin secretions
Digestive epithelia, & secretions
Figure 14-9 (1 of 7)

3. Nonspecific Defenses Phagocytes Microphages (neutrophils, eosinophils)
Macrophages
Figure 14-9 (2 of 7)

4. Nonspecific Defenses Immunological Surveillance NK cells
Find, kill cancer and virus-infected cells
Figure 14-9 (3 of 7)

5. Nonspecific Defenses Interferons
Small proteins released by virus-infected cells
Cytokines that trigger release of anti-viral proteins that inhibit virus production
Figure 14-9 (4 of 7)

6. Nonspecific Defenses Complement System Complex system of proteins
Stimulate inflammation, attract phagocytes
Figure 14-9 (5 of 7)

7. Nonspecific Defenses Inflammatory Response
Coordinated non-specific response to tissue injury
Figure 14-9 (6 of 7)

8. Nonspecific Defenses Fever Temperature greater than 99ºF
Stops pathogens
Increases metabolism
Figure 14-9 (7 of 7)