1. Nat. Rev. Cardiol. doi:10.1038/nrcardio.2016.57
Figure 5 Management of severe aortic stenosis requiring surgery, with concomitant mitral regurgitation
Figure 5 | Management of severe aortic stenosis requiring surgery, with concomitant mitral regurgitation. Mitral regurgitation is highly likely to improve with aortic valve replacement in the absence of atrial fibrillation, left atrial dilatation, or pulmonary hypertension. This algorithm requires validation by further studies. *A staged approach is possible, consisting of TAVI followed by implantation of a MitraClip® (Evalve, Inc., USA) if symptomatic mitral regurgitation persists. SAVR, surgical aortic valve replacement; TAVI, transcatheter aortic valve implantation. Modified from Nombela-Franco, L. et al. Significant mitral regurgitation left untreated at the time of aortic valve replacement: a comprehensive review of a frequent entity in the transcatheter aortic valve replacement era. J. Am. Coll. Cardiol. 63 (24), 2643–2658 © (2014), with permission from Elsevier.
Modified from Nombela-Franco, L. et al. Significant mitral regurgitation left untreated at the time of aortic valve
replacement: a comprehensive review of a frequent entity in the transcatheter aortic valve replacement era.
J. Am. Coll. Cardiol. 63 (24), 2643–2658 © (2014), with permission from Elsevier
Unger, P. et al. (2016) Pathophysiology and management of multivalvular disease
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