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Volume 140, Issue 1, Pages (July 2011)

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Presentation on theme: "Volume 140, Issue 1, Pages (July 2011)"— Presentation transcript:

1 Volume 140, Issue 1, Pages 117-126 (July 2011)
Maintenance Therapy With Continuous or Switch Strategy in Advanced Non-small Cell Lung Cancer  Xinji Zhang, PhD, Jiajie Zang, PhD, Jinfang Xu, PhD, Chong Bai, MD, PhD, Yingyi Qin, MASc, Ke Liu, PhD, Cheng Wu, PhD, Meijing Wu, PhD, Qian He, PhD, Shanshan Zhang, PhD, Lixin Wei, PhD, Jia He, PhD  CHEST  Volume 140, Issue 1, Pages (July 2011) DOI: /chest Copyright © 2011 The American College of Chest Physicians Terms and Conditions

2 Figure 1 Identification process for eligible studies. CAI = caboxyaminoimidazole; CCRT = concurrent chemoradiotherapy; HR = hazard ratio; MACC = methotrexate, doxorubicin, cyclophosphamide, and lomustine; MIC = mitomycin-ifosfamide-cisplatin; OS = overall survival; PFS = progression-free survival; RCT = randomized controlled trial; RT = radiation therapy. CHEST  , DOI: ( /chest ) Copyright © 2011 The American College of Chest Physicians Terms and Conditions

3 Figure 2 Comparison of OS between continuous maintenance therapy and placebo or observation. See Figure 1 legend for expansion of abbreviations. CHEST  , DOI: ( /chest ) Copyright © 2011 The American College of Chest Physicians Terms and Conditions

4 Figure 3 Comparison of OS between switch maintenance therapy and placebo or observation. See Figure 1 legend for expansion of abbreviations. CHEST  , DOI: ( /chest ) Copyright © 2011 The American College of Chest Physicians Terms and Conditions

5 Figure 4 Comparison of PFS between continuous maintenance therapy and placebo or observation. See Figure 1 legend for expansion of abbreviations. CHEST  , DOI: ( /chest ) Copyright © 2011 The American College of Chest Physicians Terms and Conditions

6 Figure 5 Comparison of PFS between switch maintenance therapy and placebo or observation. See Figure 1 legend for expansion of abbreviations. CHEST  , DOI: ( /chest ) Copyright © 2011 The American College of Chest Physicians Terms and Conditions

7 Figure 6 Summary of drug-related toxicities of grade 3 or greater. Alt = alanine aminotransferase. CHEST  , DOI: ( /chest ) Copyright © 2011 The American College of Chest Physicians Terms and Conditions


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