1. Mike Jepson and Paul Humphreys
MTP INNOVATIONS Ltd
Mike Jepson and Paul Humphreys

2. DIFFX Disinfection Sachet (Features & Benefits)
Powerful disinfection system
Fully enclosed soluble sachet
Non-corrosive
Environmentally friendly
100% biodegradable
Microfibre friendly
Active peracetic acid
Sporicidal
Kills MRSA & Norovirus
Kills Mycobacteria (TB) and spores of C.Diff in ALL conditions

3. DIFFX Disinfection Sachet
SACHET TESTS
EN1276 – Suspension Bacterial test
EN1650 – Suspension Fungal test
EN13697 – Surface Disinfection Test (adapted for Spores)
EN13704 – Suspension Sporicidal Test
EN14348 – Suspension Mycobacterium test
EN14476 – Suspension Viral Test (also modified for Norovirus)
Hospital Infection Research Laboratory Verification by Tina Bradley

4. The National Hospital Trial
8 week trial, standard cleaning using cloths and mops to test the anti-microbial effectiveness of DIFFX. 10 TVC’s measured at critical points around a bed and a WC. TVC’s 1 hour post cleaning reduced by 40% using standard cleaning and 90% using DIFFX
Used mops and cleaners gloves contamination was significantly reduced using DIFFX, compared to standard cleaning
Conclusion was DIFFX was novel, safe, cost effective, easy to use and effective PAA based product for hospital cleaning and disinfection
June 2012, further 8 week trial evaluating user acceptability with the new refined, reduced odour DIFFX
Conclusion was that the new product was as good as the previous trial regarding cleaning and disinfection. Domestic teams and ward staff were very happy with the product and the new low odour was more than acceptable

6. DIFFX/Chlorine Product Comparison
8 WEEK STUDY

7. Introduction
A combination of on-site sampling and laboratory studies were used to compare the performance of DIFFX and Chlorine Dioxide
The aim of the study was to determine if DIFFX was as good or better at sanitising floors and high contact surfaces than the Chlorine Dioxide

8. The Study Three investigations performed:
Comparison of before and after TVCs on a range of high contact surfaces and floors within two wards
Ward A
Ward B
Bench top wiping of bench surfaces contaminated with C. difficile spores.
Bench top wiping of bench surfaces contaminated with Staphylococcus epidermidis.

9. Hospital Study Crossover design 4 weeks on both wards
10 surfaces per ward
TSA contact plates with neutraliser employed before and immediately after cleaning
Neither product expected to have residual activity

10. Study Design Study Protocol/Weeks Weeks 1 2 3 4 5 6 7 8 Ward 1
Standard
Diff-X
Ward 2
Sampling Locations
Blue stands behind the beds
Radiator tops
Service panel behind bed
Door handle
Windowsill
Patient table
Floor - middle of ward
Floor - between the beds
Floor - side of bed
Floor -main entrance

11. Results DIFFX consistently reduced TVCs
Chlorine product results more variable
Rapid recontamination of surfaces evident

12. Conclusions
No obvious difference between 1:3 DIFFX and Chlorine based product in laboratory tests
However, in ward based trials DIFFX performed better than the Chlorine based product
Poor performance of Chlorine product likely to be due to how it is being used and the levels of organic contamination it is experiencing
DIFFX appears to be more robust and less likely to be affected by poor application and use
DIFFX at 1:1 = 100% removal of spores over 0.75m2

13. Product Inter-comparison: DIFFX vs Chlorclean (1000 ppm available Chlorine) and Haztabs (10,000 ppm available Chlorine).