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SURGERY OF THE PENIS AND URETHRA
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Agenesis Penis Congenital Anomaly : Micropenis/Microphallus
Buried Penis (Concealed/Hidden/Trapped) Phimosis Paraphimosis Hypospadias Epispadias
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Infection of the penis : balanopostitis
Penile Cancer Urethritis Urethral Stone Urethral Strictures
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Phimosis Description inability to retract the foreskin
phimosis at the first few years is physiologic the foreskin cannot be retracted after it has previously been retractable pathologic phimosis by age 3.5 years, most foreskins can be retracted
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10 % of boys have non retractile foreskin 1 % at puberty
Epidemiology 10 % of boys have non retractile foreskin 1 % at puberty Signs and symptoms discharge, soiling of undergarment irritation, cracking, bleeding from foreskin Pathophysiology Physiologic phimosis the glans penis is adherent to the prepuce in infants glandular secretions and smegma facilitate separation
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Pathologic phimosis cicatricial preputial ring (from irritation result in inflammation and scarring) : poor local hygiene, chronic balanitis (Diabetes Mellitus), early forceful retraction of foreskin balloon during voiding
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Pathologic phymosis Risk factors / causes poor hygiene, chronic
balanopostitis, diabetes mellitus Complications infection, increased risk of penile cancer
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Defferential Diagnosis
physiologic phimosis pathologic phimosis post circumcision phimosis
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History hygiene problems ? history of balanopostitis ? history of diabetes mellitus ? ballooning of foreskin when voiding ? post – void dribbling ? has there been a prior circumcision ? could the foreskin be previously retracted ?
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Physical Examination Classification of retractability of the foreskin 0 : full retraction 1 : full retraction, tight behind glans 2 : partial exposure of the glans 3 : partial retractil, meatus just visible 4 : slight retraction, unable to visualize meatus 5 : no retraction
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frenular lacerations preputial fissure cicatricial band inflammation or active infection “foreskins pearl” / smegma collection evidens of malignancy
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Laboratory testing serum glucose to evaluate for diabetes culture and sensitivity of the subpreputial space Imaging : none Special studies : none
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Physiologic phimosis encourage good hygiene gentle cleaning of smegma instruct parents in gentle and gradual retraction of prepuce never circumcise in patient with hipospadias, prepuce may needed for reconstruction
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Pathologic phimosis good hygiene steroid ointment infection antibiotics systemic or topical
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Phisiologic phimosis Treatment Medical
local steroid application ( topical vs injection ) nonsteroidal drug application ( cream ) Surgical Phisiologic phimosis circumcision ( not absolutely indicated ) surgical correction of phimosis with preservation of the foreskin
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Pathologic phimosis circumcision standard of care preputial dilatation dorsal / ventral slit surgical correction with preservation of foreskin
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Alternative therapies : none
Patient education : none Monitoring post circumcision Post circumcision phimosis inadequate primary procedure, post procedure scarring may occure with Gomco clamp, Guillotin techniques requires surgical revision glandular hyperaesthesias ( take several month after circumcision / epithelium develops squameus keratinized layer
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Complication of circumcision
is low ( 0,2 % - 0,6 % ) hemorrhage infection avascular necrosis meatal stenosis fibrous bridge
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urethrocutaneus fistula
concealed penis penile denudation lymphedema penile Prevention : none Associated condition : diabetes mellitus
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Paraphimosis Discription
Discription Painful swelling of the foreskin distal to a phimotic ring after retraction of the foreskin for a prolonged period.
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The foreskin is retracted behind the glans
Pathophysiology In children A congenital narrowed preputial opening is present The foreskin is retracted behind the glans penis and not promptly reduced Entrapment in the coronal sulcus occurs secondary to swelling of the glans This lead to venous congestion, edema, and enlargement of the glans, followed by arterial occlusion and necrosis of the glans
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In adults Typically occurs in elderly men and may be associated with poor hygiene and/or chronic balanoposthitis This iflamation leads to a contraction of the opening prepuce and forms a fibrotic ring of tissue
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the foreskin is retracted behind the glans
This in turn leads to constriction when the foreskin is retracted behind the glans Result in venous congestion with edema Failure to promptly reduce the paraphimosis can result in arterial occlusion and necrosis of the glans penis. This constitutes a urologic emergency
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Cause/risk factor Phimosis Chronic balanoposthitis Chronic indwelling Foley catheterization and catheter changes Patients requiring clean intermittent catheterization Complication Necrosis of glans and distal urethra
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Differential diagnosis
Balanitis Balanoposthitis Angioneurotic edema Anasarca edema
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Hystory Has the patient been circumcised ? Recurrent bouts of chronic balanitis ? Chronic indwelling Foley catheterization ? Clean intermittent catheterization ? Diabetes mellitus : may be risk factor for phimosis Phimosis ?
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Physical examination Edema and swelling of penile shaft proximal to the glans and corona Thick phimotic ring proximal to corona Late finding : swelling of the glans, venous congestion, necrosis of the glans penis.
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Laboratory Testing Not usually necessary If surgery planned, preoperative laboratory studies, including coagulation factors Imaging: Chest film, if surgery planned General Measures Considered urologic emergency Delay in reducing paraphimosis can result necrosis of the glans
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Medical Gentle steady pressure to foreskin to decrease swelling (May use elastic wrap or Kerlix bandage) Push the glans with thumbs, pulling the foreskin forward over the glans with the fingers ( Use the gauze pad to facilitate traction on the foreskin )
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gauge needle is used to make multiple
As an adjunct to simple reduction, a 25 – gauge needle is used to make multiple stab wounds in the edematous foreskin to help remove edema fluid May use 2 % lidocaine gel for local anesthetic Hyaluronidase 1 cc ( 150 U/cc Wydase ) injected into the one or more sites in the edematous prepuce
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Surgical Dorsal or ventral slit using 1 % lidocaine penile block Convert to normal circumcision
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Follow – Up Circumcision should be performed when the edema/inflammation resolves If there is no definitive treatment, paraphimosis tends to recur Debridement of necrotic tissue is rarely indicated
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When inserting or changing Foley catheters or performing clean
Prevention When inserting or changing Foley catheters or performing clean intermittent catheterization, reduce the foreskin after the procedure is completed
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Hypospadias Description Common urogenital malformation in
males, characterized by incompletely formed urethra wherein the misplaces meatus variably opens on the ventral aspect of the penis, scrotum, or perineum.
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Commonly associated with chorde
Malformation varies greatly in severity, ranging from the extreme form of perineal hypospadias with genital ambiguity to mild distal glans hypospadias. Commonly associated with chorde (abnormal curvature of the penis) in 50 % of the cases and/or meatal stenosis 30 % of cases.
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Epidemiology Incidence 1 in 300 live male births More common in Whites than in Blacks, and in Italians and Jews than in other ethnic groups Genetics Familial tendency 8 % of fathers of affected children have hypospadias, 14 % of male siblings affected
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Staging Classification Based on location of meatus : glans, subcoronal, penile, penoscrotal, scrotal, perineal Distal hypospadias (subcoronal or penile) comprises 60 % of cases
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Sign and Symptoms Associated anomalies Undescended testicle: 9 % Inguinal hernias: 9 % Clinically significant upper tract anomalies ; rare Chordee Chordee can occur without hypospadias, but is rare ( 0,6 % )
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Pathophysiology Unknown, but several factors involves Alterations of urethral fold closure result in hypospadias Testosterone biosynthetic defects occur in half proximal hypospadias
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Exposure to synthetic “ endocrine
disrupters” that block the effect of testosterone is critical from 9 to 12 weeks gestation Related to low birth rate in discordant monozygotic twins
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Cause/Risk Factors Unknown, some suggestion of familial risk Complications Infertility Psychological trauma ( Cosmetic )
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Differential Diagnosis
Glandular Subcoronal Penile Penoscrotal Scrotal Perineal
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History : any family history ?
Physical Examination The urethral opening may be anywhere along the shaft of the penis or into the perineum, 62 % of the openings subcoronal or penile, 22 % penoscrotal angle, and 16 % scrotum or perineum Severe proximal hypospadias may be confused with intersex disorders The more proximal meatus, the more the ventral curvature (chordee) will be seen Undescended testes and inguinal hernia
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Laboratory testing If surgery planned Imaging Incidens of upper urinary tract abnormalities is rare. With more severe ( proximal ) cases of hypospadias, some recommended screening the upper tract
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Treatment General measures With any suspicion hypospadias, neonatal circumcision should not be perfomed Many consider severe hypospadias to be a type of intersex disorder
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Surgery Treatment of the hypospadias is surgical repair and the timing of repair is best between 6 and 18 months Current techniques are superior than the older techniques Short – term follow – up examinations for development of fistulas/stricture Alternative therapies is psychosocial support as part of overall care
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Epispadias Description
Description Development abnormality wherein the urethra opens on the dorsum of the penis.
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Epidemiology 1 in newborn boys 1 in newborn girls Male – to – Female ratio : 5 : 1
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Signs and symptoms Male Urethra opens anywhere from under pubic to the tip of penis The complete or penopubic epispadias is most common
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Female Urethra opens from bladder neck to tip of urethra Most severe and common type Labia may obscure the epispadias in female
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Pathophysiology Absence of urinary sphincters in
complete type(penopubc) in males and type III in female Short, widened penis with dorsal chordee
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Urethra most commonly as
base of penis under pubic, opening can be on shaft or also on glans Bifid clitoris, separated and rudimentary labia minora Wide pubic diastasis; usually not as wide as in bladder exstrophy
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Cause/Risk Factor Unknown Complication Urinary incontinence Upper tract damage Infertility
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Differential diagnosis
Classic bladder exstrophy Lesser degrees of epispadias History Family history of epispadias
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Physical examination Pubic diastasis Position of testes
Present of any degree of bladder prolapse or exstrophy
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Laboratory testing CBC, serum electrolytes Imaging Plain X – Ray of pelvis to determine pubic diastasis Renal ultrasound to assess presence of two kidneys and presence/absence hydronephrosis
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Treatment General measure : Careful, overall examination of infant Surgical Objectives Preservation of upper urinary tract Reconstruction of functional and cosmetically acceptable external genitalia Achievement of urinary continence
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Female Repair of urethra and genital reconstruction at around 12 months of age Bladder neck repair
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Male Epispadias repair at 6 – 12 months of age after testosterone stimulation ( 3 mg/kg IM 2 weeks before surgery ) Bladder neck repair at 4 to 5 years of age when bladder capacity is adequate and child is participate in postoperative voiding program
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Follow - up after epispadias repair
Urethral stent removed 10 – 12 days after surgery Renal and bladder ultrasound at 4 months after surgery Urine cultures at three monthly interval Yearly cytoscopies and bladder capacity measurement under anesthesia until bladder capacity adequate for bladder neck repair
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Follow - up for bladder neck repair
Clamp the suprapubic tube at 3 weeks after surgery and begin voiding trial Removal of suprapubic tube when urine residuals are lees than 15 cc and child is voiding well Cytoscopy and placement of small (8 Fr) urethral catheter if child cannot voiding well
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Renal and bladder ultrasound prior
to removal of suprapubic tube and again a 3 and 12 month after surgery Antibiotic prophylaxis until follow – up shows nonreflux and child is voiding well
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Urethral Stricture Description narrowing of the urethral lumen /
Description narrowing of the urethral lumen / a scar within the urethra 60 – 70 %, in the bulbar urethra
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Etiology Congenital : rare, soft, often without spongiofibrosis 2. Infection / inflammation : Urethritis ( GO, TBC and Clamydial ) may involve long segment, include bulbar urethra.
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3. Traumatic the most common type blunt perineal “ straddel injury “ where urethra is trapped against the symphysis pubis usually partial tear
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4. Iatrogenic : instrumentation
( urethrocystoscopy, transurethral resection prostatectomy, catheterization ), usually found at meatus or penoscrotal junction.
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pelvic fracture : traffic accidents or
industrial injuries 10 %, pelvic fracture will have urethral injury, which may vary from simple contusion through partial tear to complete transection with separation of the urethral end.
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penetrating : gunshot wounds
degree of tissue injury according to projectile and velocity
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Symptoms and Signs decrease urinary stream ----more common spraying, double stream postvoiding dribbling mild dysuria hematuria urinary tract infection urethral bleeding
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urethrocutaneus fistula induration in the area of the stricture
epididymitis chronic prostatitis cystitis urethrocutaneus fistula induration in the area of the stricture periurethral absces palpable bladder ( urinary retention )
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Physical examination usually no specific findings evidence of epididymitis palpable bladder small meatal
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Imaging retrograde urethrography urethrogaphy bipolar/voiding urethrocystography IVU ( upper urinary tract evaluation and pelvic bone)
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Special studies Endoscopy : urethroscopy allows direct visualization of the stricture Uroflowmetry : may indicate obstructive pattern
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Laboratory testing nothing special, except as
indicated ( urine culture / infection ) blood analysis for preoperative care
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false passages ) Treatment Conservative : urethral dilatation ( cause
Surgical Endoscopy :Internal urethotomy (Sachse) or blind Otis Conventional (open surgical) : meatal stricture : meatotomy, meatoplasty long urethral strictures : two and multiple stage repairs
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