1. Association québécoise des médecins du sport Androgenic Anabolic Steroids

2. Association québécoise des médecins du sport Anabolic Agents Testosterone (natural hormone) Synthetic hormones Prohormones

3. Association québécoise des médecins du sport DESIRED EFFETCS Performance : Muscle power and strenght Body image : Muscle volume

4. Association québécoise des médecins du sport WHY USE THEM? Performance Appearence Both Steroids (n=45) Steroids (n=45) 45 % 24 % 31 %

5. Association québécoise des médecins du sport Therapeutic use Anabolic hormone (tissu build up) Androgenous hormone (masculinising) MECHANISM OF ACTION

6. Association québécoise des médecins du sport AAS synthetic (nandrolone, THG, …) Prohormones (DHEA, …) Subcategories of Steroids

7. Association québécoise des médecins du sport Manufacturing diagram of steroids Cholesterol 17 Hydroxyprogenenolone Dehydroepiandrosterone (DHEA) 5-Androstenediol 17 Hydroxyprogesterone Androstenedione Testosterone Dihydrotestosterone 4-Androstenediol Estrone Estradiol Pregnenolone Delta-5 Pathway Progesterone Delta-4 Pathway = Enzyme * The Physician and Sport Medecine (vol. 29, no 5, May 2001)

8. Association québécoise des médecins du sport Real Benefits AAS + adequate can increase body weight (lean mass) In some individuals : Gains in muscle strenght acquired thru intense exercise and an adequate diet can be increased by AAS

9. Association québécoise des médecins du sport Long and short term effects Some may be irreversible? Modifying factors Products used Dose and lenght of time the product is used Site of administration Individual results Health Risks

10. Association québécoise des médecins du sport Growth being stopped Inflammation and tendon rupture Problems due to salt and water retention Health Risks Musculo -skeletal

11. Association québécoise des médecins du sport Health Risks(aesthetics) Acne Gynecomasty Harsh voice (women) prematured androgenic alopecia

12. Association québécoise des médecins du sport Health Risks Reproductive System number of spermatozoids Testicular atrophy Infertility Irregular menstrual cycle Clitoris enlargement

13. Association québécoise des médecins du sport () Health Risks (psychological) agressivity Libido Infertility Withdrawal reaction

14. Association québécoise des médecins du sport (hepatic / liver) Health Risks Function abnormalities jaundice tumors cysts

15. Association québécoise des médecins du sport Health Risks (cardiovascular) Cholesterol High blood pressure Hearth attack

16. Association québécoise des médecins du sport CONCLUSION Illegal Banned Possible benefits vs enormous risks