1. Cannabis in medicinal use

2. History
Cannabis has been used for medicinal purposes for over 4,800 years
Early doctors used it for a variety of illnesses and ailments

3. History
It has been used in gastrointestinal disorders, insomnia, headaches and as a pain reliever, frequently used in childbirth
In India, cannabis can be definitely identified in such contexts only from about 1000 AD.

4. History
In 19th century Euoropean doctors used cannabis to treat melancholia, migraines, and as a sleeping aid, analgesic and anticonvulsant
In 1943 cannabis was excluded from USA’s pharmacopoeia

5. Biochemical effects
There are about a dozen different substances in marijuana that are psychoactives
The most prevalent psychoactive substance in cannabis is delta-9-tetrahydrocannabinol commonly known as THC

6. Biochemical effects

7. Biochemical effects
Cannabinoidic receptors are spread throughout the whole nervous system and are some 500 million years old.
Cannabis also contains compounds called the Cannaflavins. These compounds have been suggested to contribute certain effects of cannabis, such as analgesia and anti-inflammatory properties, and are considerably more effective than aspirin

8. Physiological effects
Cannabis has several proven medicinal purposes:
- Pain reliever
- Reduction of nausea and vomiting
- Increase of appetite
- Reduce of intraocular pressure (glaucoma)

10. Addictivity Research made by the French health comission in 1998
- most addictive and lethal: heroin, cocaine and alcohol
- second group: benzodiazepine, hallucinogens and tobacco
- least addictive and lethal: cannabis

11. Side effects
THC lowers the testosterone levels, impairs sperm production, mobility and viability
Disrupt the ovulation cycle and decreases the output of gonadotropic hormones
Lack of focus, short-term memory loss
Enhanced cancer risk

12. Methods of use Filtered/unfiltered cigarettes bongs vaporizers
eating cannabis
cannabis-based medicines