1. Progress of the new irradiation platform at LIPSION (and more)
Charlotta Nilsson
T. Reinert, T. Butz
University of Leipzig

2. The LIPSION facility
3.5 MV SingletronTM accelerator, horizontal beam line, protons or alphas, E<3 MeV (cell irradiation: E=2.25 MeV), focused beam spot size ca. 100 nm (low current mode), vertical Petri dish arrangement

3. News New chamber New translation stage New irradiation platform
New software

4. The new chamber

5. The new translation stage

6. The new irradiation platform
Still not finalized...
Reconstruction of the entire irradiation stage will start this autumn
New sample holder & Interior of the chamber
Design new Petri dish – perhaps even intelligent...
Make arrangements for CO2 inlet and temperature regulation
How/where to place the microscope/the detector?

7. The new software Control the new translation stage
Targeted irradiation of living cells:
1. Cell recognition
2. Beam control / Automated cell irradiation

8. Programming – the first baby steps
C++/Visual C++ for stage control and beam control
ImagePro Plus for cell recognition
New approach...!

9. New approach Beam control: Real-time system sockets Control system
(Linux RTAI)
sockets
Control system
(Windows)
C++
QT, ACE
sockets
Delivers target coord.
Stage controller
ImagePro Plus

10. My tasks
Participation in the completion of the new irradiation platform (especially creating an irradiation stage, testing the translation stage)
Programming of the control software for the translation stage (I get help from Silvio Perticoni!) – later on also cell recognition
Assume some responsibility for the cell culturing... I‘m trying to learn from Anja Fiedler!

11. ...and some news from Lund...
3 years in Leipzig, 1 year in Lund –> Swedish Ph. D.
Activities in Lund so far:
Courses taken in Cellbiophysics, Nuclear probes and ion beams in the materials and life sciences, Experimental methods in nuclear physics, ...
„Evaluation of a pre-cell hit detector for the future single ion hit facility in Lund“ – presented at IBA17, Sevilla, 2005

12. „Evaluation of a pre-cell hit detector for the future single ion hit facility in Lund“
silicon transmission detector, 9 µm, 2*2 mm2
Recommended bias = 2 V (leakage current = 20 nA)
Signal-to-noise ratio
Efficiency
7 different biases: 0, 2, 5, 10, 20, 50 and 70 V

13. Experiments
A Hamamatsu photo diode (stop detector) placed 4 cm behind the silicon detector
2.55 MeV protons, 4800 protons/second
The signals from the two detectors were amplified, pulse-shaped and fed into different ADCs.
The triggering required coincident signals from the two detectors.

14. Results – Signal-to-noise ratio

15. Results – Efficiency & Conclusion
Signal-to-noise ratio ok
Efficiency too low
Optimising the geometry may help improving the efficiency
Test of the beam scattering in the detector using CR-39 needed
Can the detector serve as vacuum window?