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Antidiarrheals, Laxatives, and Such…

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Presentation on theme: "Antidiarrheals, Laxatives, and Such…"— Presentation transcript:

1 Antidiarrheals, Laxatives, and Such…
By Alaina Darby

2 When 8.85L of fluid is reabsorbed in the intestine and colon, what is the excretion considered?
Constipation Normal Diarrhea b

3 When 8.8L of fluid is reabsorbed in the intestine and colon, what is the excretion considered?
Constipation Normal Diarrhea b

4 When 8.935L of fluid is reabsorbed in the intestine and colon, what is the excretion considered?
Constipation Normal Diarrhea a

5 Which of the following absorbs the most fluid from the gut? Duodenum
Jejunum Ileum Colon b

6 Sally is taking tetracycline for a bacterial infection
Sally is taking tetracycline for a bacterial infection. Which of the following laxatives would she need to avoid? Metamucil Mitrolan Citrucel Cologel b

7 Rick is taking warfarin and is constipated
Rick is taking warfarin and is constipated. Which of the following bulk forming laxatives would he need to avoid? Metamucil Mitrolan Citrucel Cologel a

8 Hannah has constipation and has started taking a bulk forming laxative
Hannah has constipation and has started taking a bulk forming laxative. She has developed an allergic reaction and her stomach has begun frequently gurgling. Which laxative is she most likely taking? Cologel Doxinate Effer-syllium Mitrolan c

9 Sandy is pregnant and in her third trimester
Sandy is pregnant and in her third trimester. She is constipated and is needing a laxative. Which of the following should she not take? Doxinate Colace Neolid Poloxame c

10 Which of the following is a non-ionic surfactant? Doxinate Surfak
Poloxamer Castor oil c

11 Judy is constipated but is also experiencing abdominal pain, nausea, and vomiting. Which of the following is a surfactant laxatives that would be suitable for her? Doxinate Surfak Poloxame Castor oil d

12 Increased permeability of intestinal mucosa
Which of the following is not a mechanism of action for stimulant laxatives? Increased permeability of intestinal mucosa Inhibition of prostaglandin synthesis Increased intestinal secretions Back diffusion of water and electrolytes b

13 Which of the following laxatives would be most potent? Citrucel
Doxinate Dulcolax Citroma c

14 Suzie has developed abdominal pain nephritis and pink urine
Suzie has developed abdominal pain nephritis and pink urine. What laxative is she taking? Senokot Modane Dulcolax Citrucel a

15 Which of the following osmotic laxatives also increases cholecystokinin?
Visicol Cephulac Citroma Golytely c

16 Which of the following is not a magnesium containing laxative?
Epsom salt Cephulac Milk of magnesia Citroma b

17 Which of the following is a phosphate containing laxative that is given prior to colonoscopy?
Golytely Visicol Cephulac Lubiprostone b

18 Which of the following osmotic laxatives also acidifies the urine?
Visicol Cephulac Citroma Golytely b

19 Which of the following describes the action of lubiprostone?
Activates intestinal chloride channels to increase secretion and mobility Activates intestinal chloride channels to decrease secretion and mobility Activates intestinal calcium channels to increase secretion and mobility Activates intestinal calcium channels to decrease secretion and mobility a

20 Increased osmotic load in the intestine
Which of the following is not a mechanism through which diarrhea is caused? Increased osmotic load in the intestine Excessive secretion of electrolytes and water Decreased absorption of protein and fluid to the mucosa Increased intestinal motility c

21 Which of the following would not be advised in the event diarrhea caused by an invasive organism?
Amphogel Charcoal Pepto-bismol Metamucil a

22 Which of the following would be effective to prevent Traveler’s diarrhea?
Amphogel Charcoal Pepto-bismol Metamucil c

23 Which of the following opioids is available over- the-counter?
Diphenoxylate with atropine Loperamide Codeine phosphate and sulfate Paregoric b

24 Which of the following is not a mechanism of opiates?
Decrease secretions Decrease motility Decrease sphincter muscle tone Decrease cramps c

25 They are used as anti-spasmotics to alleviate cramps
What is the following is not true of anticholinergic antidiarrheal agents? They are used as anti-spasmotics to alleviate cramps Propantheline can be used for urinary retention These agents may cross the BBB to produce CNS side effects Phenobarbital + atropine (Donnatal) is available over the counter c

26 Maintain nutritional status Correct the underlying condition
Which of the following is not a goal for inflammatory bowel disease treatment? Control inflammation Reduce morbidity Maintain nutritional status Correct the underlying condition d

27 Which of the following acts as a local anti- inflammatory agent?
Sulfasalazine Mesalamine Olsalazine Sulfapyridine b

28 Which of the following causes adverse effects such as anemia, rash, and impotence in its present form? Sulfasalazine Mesalamine Olsalazine Sulfapyridine d

29 Which of the following begins to be released in the jejunum?
Mesalamine DR capsules Mesalamine pH-sensitive Release tablets Olsalazine Sulfasalazine a

30 Mercaptopurine and entanercept Infliximab alone
Which of the following is typical treatment for inflammatory bowel disease? Mercaptopurine and entanercept Infliximab alone Mercaptopurine and infliximab Infliximab and entanercept c

31 Which of the following is true of portal systemic encephalopathy?
It is a consequence of renal failure It is an increase in blood ammonium levels It can be treated with neomycin to reduce bacteria in the colon It can be treated with lactulose to alkalize the urine c

32 Which of the following is not true of GERD?
Associated with relaxation of the lower esophageal sphincter Increased gastric emptying is common Incompetent sphincter function is common Esophageal mucosa has impaired resistance to injury b

33 Which of the following describes Barrett’s esophagus?
It is the name for a stricture in the esophagus It is the name for patches cancerous tissue in the esophagus It is the name for severe erosion and deep ulcerations in the esophagus It is the name for growth of the stomach lining into the esophagus d

34 Which of the following is not a therapy to primarily treat the condition that concerns the readiness of gastrointestinal contents to reflux? Eat smaller meals Prokinetic drugs Bed elevation Avoidance of coffee b

35 Eric has Parkinson’s and is experiencing recurring heartburn
Eric has Parkinson’s and is experiencing recurring heartburn. Which of the following medications would he be least likely to take? Ranitidine Metoclopramine Omeprazole Famotidine b

36 Doug has begun taking metoclopramine for his recurring heartburn
Doug has begun taking metoclopramine for his recurring heartburn. Which of the following would not be contraindicated for him to take with this prokinetic treatment? Tranycypromine Phenelizine Cimetidine Isocaraboxazid c

37 Which of the following is not a mechanism of metocloparmide?
D2 receptor blockade Release of acetylcholine Inhibition of serotonin release 5HT­­­4 Receptor agonism c

38 Stimulate GI smooth muscle Accelerate gastric emptying
Which of the following is not a pharmacological action of metocloparamide? Stimulate GI smooth muscle Accelerate gastric emptying Decrease LES pressure Increase esophageal contractions c

39 Steven is excreting 240mL of fluid in his stool
Steven is excreting 240mL of fluid in his stool. He has just visited a foreign country where he is believed to have gotten a parasite that is causing this issue. Which of the following might be beneficial to him? Castor oil Lactulose Paregoric Metamucil d


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