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Antidotes Intro pharm section FA.

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Presentation on theme: "Antidotes Intro pharm section FA."— Presentation transcript:

1 Antidotes Intro pharm section FA

2 Acetaminophen

3 N-acetylcysteine (replenishes glutathione)

4 AChE inhibitors, organophosphates

5 Atropine followed by pralidoxime

6 Amphetamines

7 NH4Cl Amphetamines are bases, so adding NH4Cl would acidify the urine and trap the amphetamines as ionized formthey get excreted

8 Antimuscarinic, anticholinergic agents

9 Physostigmine salicylate, control hyperthermia

10 Benzodiazepines

11 Flumazenil

12 Beta-blockers

13 Glucagon

14 Carbon monoxide

15 100% oxygen, hyperbaric oxygen

16 Copper, arsenic, gold

17 penicillamine

18 cyanide

19 Nitrite + thiosulfate, hydroxocobalamin

20 digitalis

21 Anti-dig Fab fragments

22 Heparin

23 Protamine sulfate

24 Iron

25 Deferoxamine, deferasirox
Fe = iron

26 Lead

27 CaNaEDTA, dimercaprol, succimer, penicillamine

28 Mercury, arsenic, gold

29 Dimercaprol (BAL), succimer, EDTA (mercury)

30 Methanol, ethylene glycol (antifreeze)

31 Fomepizole>ethanol, dialysis

32 Methemoglobin

33 Methylene blue, vitamin C

34 Opioids

35 Naloxone

36 Salicylates

37 NaHCO3, dialysis Salicylates are acidsyou want to alkalinize the urine to trap them as ions and cause excretion

38 TCAs (tricyclic antidepressants)

39 tPA, streptokinase, urokinase

40 Aminocaproic acid

41 Warfarin

42 Vitamin K, plasma (if active bleeding)


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