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Assist. Prof. Dr. Açelya Yılmazer Aktuna

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Presentation on theme: "Assist. Prof. Dr. Açelya Yılmazer Aktuna"— Presentation transcript:

1 Assist. Prof. Dr. Açelya Yılmazer Aktuna
Cell Biology BME140 Lecture 7 DNA Replication Assist. Prof. Dr. Açelya Yılmazer Aktuna

2 DNA Replication DNA Replication Occurs at Sites Called Replication Factories DNA Replication Is Semi-discontinuous Steps: Initiation Elongation Termination

3 DNA Replication Replication fork
DNA is always synthesized in the 5' to 3' direction Leading strand Lagging strant At the replication fork, many replication enzymes assemble on the DNA

4 DNA Replication DNA Helicase Replication Fork DNA Polymerase DNA clamp
Single-Strand Binding (SSB) Proteins Topoisomerase DNA Gyrase DNA Ligase  Okazaki Fragments  Primase Telomerase

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