1. A simple introduction to Science at ISIS
Robert McGreevy
ISIS Facility,
CCLRC Rutherford Appleton Laboratory,
Chilton, Didcot, OX11 0QX, UK.

6. To see small things – you need a big thing …

7. What can neutrons and muons do?
’Neutrons (and muons) tell you where atoms are and what atoms do’

8. Diamond
Graphite
Fullerene

9. Neutron Diffraction

11. Inelastic Neutron Scattering

12. Momentum – k (velocity) Energy - E Particle
Time of flight method
Momentum – k (velocity)
Energy - E
Particle
Wave
Wavelength – λ (length scale)
1000 m/s
20 m μs
20 ms
10-10 m

15. Neutrons see the world in a unique way
… to hydrogenase
From hydrogen …
Length and time scales
10-11 – 10-6 m – 10-6 s

16. Neutrons see the world in a unique way
… to hydrogenase
From hydrogen …
Length and time scales
10-11 – 10-6 m – 10-6 s

17. Neutrons see the world in a unique way

18. Neutrons see the world in a unique way
Penetration
Large samples, buried interfaces, non-destructive

19. Neutrons see the world in a unique way
Magnetism
The neutron has a magnetic moment but no charge

20. = + + Neutrons see the world in a unique way
Sensistivity and selectivity
Isotopic substitution/contrast variation

21. Neutrons see the world in a unique way
a(4K) = (2) Å
18th order spherical harmonic
c18,1 = ; c18,2 = 0.077
Precision
Weak interaction, simple interaction

23. Crystallography
Powder diffraction
HRPD
POLARIS
GEM
HiPr
(ROTAX)
WISH (TS2)
Single crystal diffraction
SXD
Engineering diffraction
ENGIN-X

24. Single crystal diffraction - SXD

25. Anticancer drug studied on SXD in 2005
C. K. Broder et al.

26. Anticancer drug studied on SXD in 2005
C. K. Broder et al.