1. OXYGEN THERAPY PROFESSOR CONOR BURKE
MD, FRCP(i), FRCP (LOND), FCCP, FFSEM
CONSULTANT RESPIRATORY PHYSICIAN
CONNOLLY HOSPITAL
MATER UNIVERSITY HOSPITAL
BONS SECOURS HOSPITAL
UNIVERSITY COLLEGE DUBLIN

2. LIFE
TISSUE OXYGEN DELIVERY
TOD = CaO2 x CO

3. BLOOD OXYGEN CONTENT DISSOLVED O2 (<1%) +
HAEMOGLOBIN BOUND O2 (>99%)

4. EVOLUTION BODY “DEFENDS” PaO2 OF 8.0 kPA INCREASED VENTILATION
HYPOPXIC PULMONARY VASOCONSTRUCTION
POLYCYTHAEMIA

5. DOMICILIARY OXYGEN
THERAPEUTIC (COPD)
PALLIATIVE

6. DOMICILIARY OXYGEN ASSESSMENT (COPD)
ABG (NOT SAT)
30 MINUTES ON ROOM AIR
8 WEEKS POST EXACERBATON
ABG TWICE 3 WEEKS APART

7. THERAPEUTIC DOMICILIARY OXYGEN
COPD ONLY
PaO2 < 7.3 kPa
PaO2 < 8 kPa +
PULMONARY HYPERTENSION
ODEMA
POLYCYTHAEMIA (Ht > 55%)

8. TITRATION START AT 1L/M AIM FOR PaO2 > 8.0 kPa
If PaCO2 INCREASES ? BIPAP
NOCTURNAL HYPOXIA
EXERCISE HYPOXIA

9. DURATION (THERAPEUTIC)
MRC TRIAL
NOT TRIAL
AT LEAST 15 HOURS DAILY

10. AMBULATORY O2
SAO2 < 90% ON 6 MWT
CLINICAL IMPROVEMENT

11. OXYGEN CONCENTRATORS DELIVER UP TO 5 (9) L/M NASAL PRONGS (CONSERVERS)
VENTURI MASK
TRANSPORTABLE

12. CYLINDERS
BACK-UP
AMBULATORY

13. SHORT BURST O2
CLUSTER HEADACHE
15 L/M (CYLINDER) FOR 30 MINUTES

14. AIR TRAVEL PaA2 > 9.3 kPa SAFE HYPOXIC CHALLENGE FEV1 < 30%
BULLOUS DISEASE
RECENT EXACERBATION (6 WEEKS)
RECENT PNEUMNOTHORAX

15. SAFETY
CIGARETTES
VAPING
CHARGING
UNDER MATERIAL
VASELINE