1. Volume 21, Issue 7, Pages 859-866 (July 2005)
Preoperative feeding preserves heart function and decreases oxidative injury in rats 
Danny E.C. van Hoorn, Petra G. Boelens, M.Sc., Mariska C. van Middelaar-Voskuilen, Robert J. Nijveldt, M.Sc., Hubert Prins, M.D., Hetty Bouritius, M.Sc., Zandrie Hofman, M.Sc., Laura M’rabet, Ph.D., Paul A.M. van Leeuwen, Klaske van Norren, Ph.D. 
Nutrition 
Volume 21, Issue 7, Pages (July 2005)
DOI: /j.nut
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2. Fig. 1
Heart function during the IR period. (A) Difference in cardiac output between IR-fasted animals and sham-fasted animals was significant (*P < 0.05) after longer than 90 min of reperfusion. (B) Difference in heart rate between the IR-fasted and sham-fasted animals was significant (*P < 0.05) after longer than 150 min of reperfusion. IR, ischemia and reperfusion.
Nutrition  , DOI: ( /j.nut )
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3. Fig. 2
Postischemic oxidative stress in the intestine. (A) Intestinal ATP levels differed significantly between the IR-fasted group and the sham-fasted group (P < 0.05). (B) Intestinal MDA concentrations differed significantly between IR-fasted and sham-fasted animals. ATP, adenosine triphosphate; IR, ischemia and reperfusion; MDA, malondialdehyde.
Nutrition  , DOI: ( /j.nut )
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4. Fig. 3
Postischemic oxidative stress in the lung. MDA concentrations in lung tissue differed significantly between IR-fasted and sham-fasted animals (P < 0.05) and between IR-fed and IR-fasted animals (P < 0.002). IR, ischemia and reperfusion; MDA, malondialdehyde.
Nutrition  , DOI: ( /j.nut )
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5. Fig. 4
Biochemical characterization of liver function. (A) A significant (P < 0.001) difference was found between IR-fed animals and IR-fasted animals and between IR-fed animals and sham-fasted animals. (B) NAD+ concentration in the IR-fasted animals was significantly lower than in the sham-fasted and IR-fed animals (P < 0.05 and P < 0.01, respectively). (C) The β-oxidation product C22:6 (ω-3) showed significant differences between IR-fed animals and IR-fasted animals (P < 0.05) and between IR-fed animals and IR-fasted animals (P < 0.01). If C22:6 (ω-3) is set to 100% for the fed group, that measurement for the sham-fasted group is 161 ± 26% and that for the IR-fasted group is 145 ± 14%. (D) Total ATP levels in liver showed significant differences between the IR-fasted group and the sham-fasted group and between the IR-fed group and the IR-fasted group (P < 0.01). (E) Energy balance, expressed as ATP/ADP ratio, showed significant differences between the IR-fasted group and the sham-fasted group (P < 0.05) and between the IR-fed group and the IR-fasted group (P < 0.01). ADP, adenosine diphosphate; ATP, adenosine triphosphate; IR, ischemia and reperfusion; MDA, malondialdehyde; NAD+, oxidized nicotinamide adenine dinucleotide.
Nutrition  , DOI: ( /j.nut )
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6. Fig. 5
Plasma glucose concentration differed significantly between the IR-fed group and the two fasted groups (P < 0.001). IR, ischemia and reperfusion.
Nutrition  , DOI: ( /j.nut )
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