1. From: Lectin from Agaricus bisporus Inhibited S Phase Cell Population and Akt Phosphorylation in Human RPE Cells
Invest. Ophthalmol. Vis. Sci ;53(12): doi: /iovs
Figure Legend:
ABL led to reduction in S-phase populations for all RPE cell lines. (A, C) The effects of ABL on G0/G1 and G2M were mixed. No significant effect was detected for the G0/G1 (A) and G2M (C) phases on the hRPE1 cells (open bars). Application of ABL in hRPE3 cells (shaded bars) reduced the G0/G1 population (A) and increased the G2M population (C). (B) S-phase population decreased after the two primary RPE cells were treated with ABL (90 μg/mL) for 3 days. (D–F) Representative flow cytometry plots for the cell cycle distribution of hRPE1 cell were shown. The amount of cells in S phase decreased with increasing ABL concentrations (arrows). Mean ± SEM; n = 3–5; *P < 0.05, **P < 0.01 versus control group.
Date of download: 10/14/2017
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