1. Need Knowledge Base Literature Review Purpose Hypothesis
The Effects of Alcohol on Short-Term Memory in Drosophila Melanogaster
Alcohol has the largest death rate out of all other drugs
disorders caused by alcohol have increased over the past 6 years
Knowledge Base
Short Term Memory
Alcohol
Olfactory training
Literature Review
LaFerriere, 07
Moore, 98
Control and chpd
Comparison between Control and chpd Drosophila
Moore, 98
Holly LaFerriere 2007
Purpose
Hypothesis
The purpose of this experiment is to demonstrate the effects of alcohol exposure on short term memory in drosophila.
Null Hypothesis: the ethanol exposure will have no effect on the short term memory of Drosophila melanogaster.
Alternate Hypothesis: the Drosophila exposed to ethanol will have impaired short term memory, and the Drosophila who are not, will not

2. Exposed to Alcohol for 5 minutes
Methodology
Wild Type Drosophila
Control
Alcohol Before
Alcohol After
Exposed to Alcohol for 5 minutes
Trained in olfactory method with one minute shock increments every 10 minutes
Tested 5 hours later
Tested 5 hours later
Tested 5 hours later
Performance index used to see if learning occurred
Training Chamber
Testing Chamber
Results

3. Discussion Limitations Conclusion Future Studies Bibliography
Ethanol beaker
Air pump
Alcohol Exposure
Exposure chamber
Discussion
The purpose of this experiment is to demonstrate the effects of alcohol exposure on short term memory in drosophila.
Results demonstrated that exposure to alcohol impaired short term memory
Performance Index: (Correct-Incorrect)-.5/.5 x100
Limitations
Conclusion
The number of trials for drosophila exposed to alcohol could have been higher and possible human errors.
Data Supported the Alternate Hypothesis
Future Studies
Effects of alcohol on long term memory.
Bibliography
Bayard, Max. "Alcohol Withdrawal Syndrome - March 15, American Family Physician." American Academy of Family Physicians May 2009 <
Ericson, Nels. "Substance Abuse:The Nation’s Number One Health Problem." U.S. Department of Justice. <
Farr, Susan. "Drinking for just eight weeks impairs learning and memory in mice." Science, Industry and Business: the innovations-report. 15 May 2009 <
Grant B, Harford TC, Dawson DA, et al. Prevalence of DSM-IV alcohol abuse and dependence, United States Alcohol Health & Research World 18(3)
Laferriere, Holly, and Douglas J. Guarnieri. "Genetic Dissociation of Ethanol Sensitivity and Memory Formation in Drosophila melanogaster." (2008). Genetics. <
Miller, Loren L., and Michael P. Dolan. "SpringerLink - Journal Article." SpringerLink Home - Main <
Moore, Monica, and Jim DeZazzo. "Ethanol Intoxication in Drosophila:Genetic and Pharmacological Evidence for Regulation by the cAMP Signaling Pathway." (1998). <