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From Accelerators Physics to Nuclear Medicine
Nhât-Tân Vuong Work Package 1: Mass separation of innovative medical isotopes
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Marie Sklodowska-Curie
1903 Marie Sklodowska-Curie
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Nuclear Medicine
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Medicis-Promed
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An Innovative Training Network
Physics Radiochemistry Engineering Medicine Biology Strength of the network MEDICIS-PROMED will train a new generation of entrepreneurial scientists to build an active collaboration between research institutions, private companies and hospitals in the Lemanic area and all across Europe. A network of world leading experts offers a unique interdisciplinary background to advance the development of applications of radioisotopes in nuclear medicine and oncology.
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The scope of the MEDICIS Project
11C based hadron therapy Production of innovative radioisotopes Diagnostic Imaging Personalized Treatment of Cancer MEDICIS = MEDical Isotopes Collected from Isolde How are we going to do that ? 1 Prod of new isotopes 2 New radiopharmaceuticals 3 Beam technology to dev. Hadron therapy Diagnostic imaging and therapy of cancer Development of Radiopharmaceuticals
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Innovative isotopes C. Muller et al. jnumed.112.107540v1
and many others…* * CERN-MEDICIS : A New Facility. R.S. Augusto et al C. Muller et al. jnumed v1 Brain 213Bi-pept Lung 177Lu-mab Liver 166Ho (microspheres) Kidney Ovary Prostate Leukemia Myeloma Ac-mab Melanoma 213Bi-mab
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Isotope production
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Isotope production Cyclotron. Arronax, Nantes FR
Nuclear reactor. ILL, Grenoble FR
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CERN 1000+ isotopes of 70+ chemical elements Nuclear Physics
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CERN-MEDICIS: a new facility
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From Accelerator Physics to Nuclear Medicine
CERN-Medicis Facility Talk about chemistry
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Production of isotopes
High energy Protons Target unit spallation fragmentation fission 1.4 GeV protons Example of target materials UC2 pellets Ta rolls
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Nano-fibrous target material
Y-ac. nanofibers Sanjib Showdhury - Portugal - Instituto Superior Técnico
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Graphene coated target material
Marina Nazarova - UK - University of Manchester
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Radioactive waste UC2 pellets U3O8
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Isotope Separator On-Line (ISOL)
1.4 GeV Protons Production of isotopes CERN CERN Accelerators CERN-ISOLDE General ISOLDE presentation ISOL technique
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Isotope separation Laser Production of isotopes CERN CERN Accelerators
Mass separation Element specific ions source Laser Production of isotopes CERN CERN Accelerators CERN-ISOLDE General ISOLDE presentation ISOL technique
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High purity laser ionization scheme
Resonance Ionization Laser Ion Source RILIS at CERN Vadim Gadelshin - Germany - Johannes Gutenberg-Universität Mainz
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Chemical separation Nhât-Tân Vuong – Switzerland - CERN
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Transportation Type A package Maddalena Maietta - France - Lemer Pax
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THANK YOU “This research project has been supported by a Marie Skłodowska-Curie Innovative Training Network Fellowship of the European Commission’s Horizon 2020 Programme under contract number MEDICIS-PROMED”
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