1. NEW GENERATION BIOMIMETIC AND CUSTOMIZED IMPLANTS FOR BONE ENGINEERING
COST Action – MP1301
NEWGEN
NEWGEN
NEW GENERATION BIOMIMETIC AND CUSTOMIZED IMPLANTS FOR BONE ENGINEERING
Dr. Francis Cambier
Vienna (AT), August 28th - 29th, 2017

2. Scientific context and objectives
Background / Problem statement:
Ageing population
Increasing expectations regarding quality of life
Increasing demand for procedures such as total hip replacements, bone reconstructions, spinal fusions…
New advances in biomaterials (improved processing, bioactivity and/or tailored shapes, enough structural integrity and bone integration/regeneration): currently under development at the laboratory scale
However: gap between academic R&D and commercial production, and between materials scientists and clinicians,
NEWGEN MoU objectives: This COST Action, NEWGEN, aims at creating the seed for the European research and industry collaboration, combining basic knowledge from academic laboratories, R&D centres, medical units from hospitals, and a significant number of companies, in the field of biomaterials to realize new functionalized, bioresorbable and customized bone substitutes and more reliable implants

3. Training School – PATRAS (Greece) – May 10th, 2017
Chair: Dr. F. Cambier (BCRC, BE)
Vice-Chair: Dr. P. Palmero (Politecnico di Torino, IT)
Biomaterial
Conception
Multi
disciplinary
Materials
Multi
Partners
 Unique opportunity to link European researchers to industries and end-users
Training School – PATRAS (Greece) – May 10th, 2017

4. Training School – PATRAS (Greece) – May 10th, 2017MC
WG1
WG2
WG3
WG4
Core Group
Design and Synthesis of New Materials
Manufacturing and Characterization of 3D-porous Scaffolds
Functionalization of implants for improved functional and therapeutic effects
In Vitro Evaluation of the Performance
8 workshops
7 calls for STSM (46 grantees up to now)
2 training schools
More than 30 scientific publications
Training School – PATRAS (Greece) – May 10th, 2017

5. First job : learning COST rules…
ECI (ESR), SO, AO, GHM, STSM, CSO, CG, MC, …
Inclusiveness targeted policy countries
Gender balance…
VADEMECUM!!!! (with a new version every year…)
E-COST system with

6. Our consortium! 2 nouveaux pays : Estonie et Bosnie Herzégovine
Inclusiveness targeted policy countries in NEWGEN

7. Our consortium! From 66 groups in the proposals in 2013,
up to 167 groups at the end of the Action!
21 European countries signed the MoU before the start of the Action
Up to now, 33 countries (on 36) joined NEWGEN
2 nouveaux pays : Estonie et Bosnie Herzégovine
Inclusiveness targeted policy countries in NEWGEN

8. Overview of the consortium - status of the Action
Start of NEWGEN : October 2nd, / End : October 1st, 2017
33 countries + 3 IPC : USA + Canada + Australia
Whole consortium
167 institutions
Universities: 89
R&D Centers: 24
Industry: 22
Medicine: 22
327 contacts in the mailing list
Gender balance = 39% / Inclusiveness = 33%

9. Overview of the consortium - status of the Action
Start of NEWGEN : October 2nd, / End : October 1st, 2017
33 countries + 3 IPC : USA + Canada + Australia
Whole consortium
167 institutions
Universities: 89
R&D Centers: 24
Industry: 22
Medicine: 22
327 contacts in the mailing list
Gender balance = 39% / Inclusiveness = 33%

10. NEWGEN : 4 Years of a large European networking on biomaterials
With organization of :
Training Schools
Workshops
STSM
Management Comittee and Core Group meetings

11. 1st Training School in Madrid
June 17th to 19th, 2015
15 lectures
60 students

12. 2nd Training School in Patras
12 lectures
35 students
Poster contest
Bone structure and properties
Cell biology, Bone physiology;
Biocompatibility; Biointerphase;
Processing of materials and final surface characteristics;
Scaffold design, processing, biodegradation/resorption;
Mechanobiology;
Bone Tissue Engineering;
In vivo experimental procedures and Surgical aspects

13. STSM: review WG 1st call (2014) 2nd call (2015) 3rd call (2015)
4th call (2016)
5th call (2016)
6th call (2016)
7th call
(2017)
Total 1 2 3 10 5 15 8 4 13
Budget (€)
18.000,00
21.450,00
8.550,00
10.800,00
13.170,00
9.000,00
3.000,00
84.670,00
Period
Là, je peux éventuellement prendre le relais quelques minutes:
Tableau 1 : nombre de grantees par call et par WG + répartition des budget pour les 6 calls
Graphe 1 : pourcentage de répartition du nombre de grantees par WG  presque équilibre! (en vert : WG3 un peu inférieur, mais moins de groupes membres du WG3 par rapport aux 3 autres)
Graphe 2 : pourcentage de répartition du budget total par WG  presque équilibre aussi!

14. STSM: review WG 1st call (2014) 2nd call (2015) 3rd call (2015)
4th call (2016)
5th call (2016)
6th call (2016)
7th call
(2017)
Total 1 2 3 10 5 15 8 4 13
Budget (€)
18 000
21 450
8 550
10 800,00
13.170,00
9.000,00
3.000,00
84.670,00
Period
Là, je peux éventuellement prendre le relais quelques minutes:
Tableau 1 : nombre de grantees par call et par WG + répartition des budget pour les 6 calls
Graphe 1 : pourcentage de répartition du nombre de grantees par WG  presque équilibre! (en vert : WG3 un peu inférieur, mais moins de groupes membres du WG3 par rapport aux 3 autres)
Graphe 2 : pourcentage de répartition du budget total par WG  presque équilibre aussi!
46 Grantees (mostly PhD and ECI), with a STSM mean duration of 40 days
84 670€ dedicated to STSM, on the 600k€ of the total budget of the Action! (15%)
High quality of reports, and leading to scientific publications ( in preparation) and oral presentations in international conferences ( planned)
A very good tool to promote mobility of young researchers

15. Workshops and meetings

16. Workshops and meetings

17. Workshops and meetings
8 workshops with invited speakers, oral presentations, poster sessions, etc.
Torino (IT)
Nantes (FR)
La Valette (MT)
Sofia (BG)
Aveiro (PT)
Zlin (CZ)
Cluj-Napoca (RO)
Vienna (AT)
5 Management Committees (Brussels, Torino, La Valette, Aveiro, Cluj-Napoca) and 6 Core Group meetings (Porto, Limerick, Riga, Stuttgart, Gothenburg, Zagreb)

18. Special thanks to all Local Organizers (1/2):
Paola Palmero (MC meeting + Workshop Torino, IT)
Fernando Monteiro (CG meeting Porto, PT)
Pierre Weiss (Workshop Nantes, FR)
Stuart Hampshire (CG meeting Limerick, IE)
Josette « Barbara » Camilleri (MC meeting + workshop La Valetta, MT)
Carmen Baudin (1st Summer School Madrid, ES)
Albena Daskalova (Workshop Sofia, BG)
Janis Locs (CG meeting Riga, LV)

19. Special thanks to all Local Organizers (2/2):
Margarida Almeida (MC meeting + Workshop Aveiro, PT)
Norbert Schneider (CG meeting Stuttgart, DE)
Nabanita Saha (Workshop in Zlin, CZ)
Gabriel Furtos (MC meeting + Workshop Cluj-Napoca, RO)
Erik Adolfsson (CG meeting Gothenburg, SE)
Yannis Missirlis (2nd Summer School Patras, EL)
Stefan Scheiner (Final Event Vienna, AT)
Andreja Gajovic (CG meeting Zagreb, HR)

20. Special thanks to WG (+ vice) Leaders and coordinators
Paola Palmero Vice-Chair
Carmen Baudin / Anne Leriche WG1
Jérôme Chevalier / Hilda Mulvihill WG2
Erik Adolfsson / Norbert Schneider WG3
Fernando Monteiro / Benjamin F. Gutierrez WG4
Anne Leriche Website Coordinator
Eamonn De Barra Dissemination Coordinator
Stephane Hocquet STSM Coordinator
Véronique Huart Grant Holder Manager